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PubMed News (NIH) 10/27/2020
Contributors : Zhaojian Gong ; Wei Xiong ; Zhaoyang Zeng ; Panchun Li Series Type : Expression profiling by array ; Non-coding RNA profiling by array Organism : Homo sapiens. Chewing betel nut is an important risk factor for the carcinogenesis of tongue squamous cell carcinoma (TSCC), but the mechanism is still unknown.To screen the lncRNAs associated with betel nut chewing-induced TSCC and identify potential biomarkers for the TSCC, we collected 5 pairs of TSCC and paracancerous tissues and monitored the resultant lncRNA and mRNA expression profiles using an lncRNA microarray.
ClinicalTrials.gov 10/26/2020 08:15
Condition : Locally Advanced Esophageal Squamous Cell Carcinoma Interventions : Drug: Sintilimab; Drug: Chemotherapy; Radiation: Radiation Therapy Sponsors : Sichuan Cancer Hospital and Research Institute; General Hospital of Ningxia Medical University; First Affiliated Hospital Xi'an Jiaotong University; Affiliated Hospital of Southwest Medical University; Chongqing Three Gorges Central Hospital Recruiting.
Oral Diseases 10/24/2020 05:37
Abstract. Objectives. To examine the prognostic significance of pre‐treatment C‐reactive protein (CRP), N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) and cardiac troponin T (cTnT) levels on all‐cause mortality three years after head and neck squamous cell carcinoma (HNSCC) diagnosis. Subjects and Methods. Data from 118 consecutive HNSCC patients, treated between 2012 and 2015, were evaluated prospectively.
BioNewsFeeds 10/23/2020 08:00
Adding UV1, Ultimovacs’ experimental cancer vaccine, to Keytruda (pembrolizumab) is safe and shows initial signs of effectiveness in adults with previously untreated metastatic melanoma, according to top-line data from a Phase 1 clinical trial. “The safety profile observed to date in this first cohort [group of patients] of the [UV1-Keytruda] combination study is consistent with the promising […]. .

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