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CD147 expression was increased in the esophageal squamous cell lines, and interference with CD147 hindered the proliferation, invasion, and migration of ESCC cells, and inhibited the growth and angiogenesis of the esophageal squamous cell line.
More from International Journal of COPD:
ClinicalTrials.gov 10/27/2020 06:39
Grade 3/4 AEs are more frequently observed (50-60% of patients) in melanoma because ipilimumab is administrated at 3mg/kg in this population.
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PubMed News (NIH) 10/27/2020
Contributors : Zhaojian Gong ; Wei Xiong ; Zhaoyang Zeng ; Panchun Li Series Type : Expression profiling by array ; Non-coding RNA profiling by array Organism : Homo sapiens. Chewing betel nut is an important risk factor for the carcinogenesis of tongue squamous cell carcinoma (TSCC), but the mechanism is still unknown.To screen the lncRNAs associated with betel nut chewing-induced TSCC and identify potential biomarkers for the TSCC, we collected 5 pairs of TSCC and paracancerous tissues and monitored the resultant lncRNA and mRNA expression profiles using an lncRNA microarray.
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Healio News 10/26/2020 16:26
Older patients with melanoma may have poorer response to anti-VEGF therapy.
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GlobeNewswire 10/26/2020 07:30
– Preclinical data support potential to expand therapeutic utility of tipifarnib to HRAS/PI3K dependent tumors representing up to 50% of HNSCC –
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Technology Org 10/26/2020 05:30
Melanoma research brings understanding of cellular resistance to cancer treatment, opening doors to new cures.
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Based on the patient’s clinical course and the appearance of melanoma metastasis, the initial cutaneous lesion was thought to require reclassification as a Spitzoid melanoma with subsequent lung metastasis.
More from Diagnostic Pathology - Abstract:
Oral Diseases 10/24/2020 05:37
Abstract. Objectives. To examine the prognostic significance of pre‐treatment C‐reactive protein (CRP), N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) and cardiac troponin T (cTnT) levels on all‐cause mortality three years after head and neck squamous cell carcinoma (HNSCC) diagnosis. Subjects and Methods. Data from 118 consecutive HNSCC patients, treated between 2012 and 2015, were evaluated prospectively.
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Biological information and functional analysis reveal the role of discoidin domain receptor 1 in oral squamous cell carcinoma.
More from International Journal of Paediatric Dentistry (EU):
News-Medical.net 10/23/2020 12:58
Age can affect response to adjuvant treatment among patients with resected melanoma.
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BioNewsFeeds 10/23/2020 08:00
Adding UV1, Ultimovacs’ experimental cancer vaccine, to Keytruda (pembrolizumab) is safe and shows initial signs of effectiveness in adults with previously untreated metastatic melanoma, according to top-line data from a Phase 1 clinical trial. “The safety profile observed to date in this first cohort [group of patients] of the [UV1-Keytruda] combination study is consistent with the promising […]. .
Immuno-Oncology News 10/23/2020 08:00
The Phase 1 clinical trial (NCT03538314), which completed enrollment in August, is evaluating the safety, tolerability, and preliminary effectiveness of adding UV1 to first-line treatment with Keytruda in 30 adults with metastatic melanoma.
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Business Wire 10/21/2020 07:00
Interpreted in the context of other clinical, laboratory and histopathologic information, ConfirmDx-Melanoma is designed to add diagnostic clarity and confidence for dermatopathologists, while helping dermatologists better understand the clinical implications for more informed patient care.
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EurekAlert 10/20/2020
New tumour formation initiated by a powerful set of signals By using melanoma cell lines and preclinical models, the team found that melanoma cells can initiate tumours at new sites via a powerful signalling cascade.
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