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Healio News 09/22/2020 18:23
In the United States, rates of COVID-19 were 1.4 times higher than the national average in counties with higher-than-average Black and Hispanic populations, according to recent data. The findings were published in the Healthiest Communities report released by U.S. News and World Report and the Aetna Foundation, an independent, charitable affiliate of CVS Health. “The COVID-19 pandemic has brought attention to the existing disparities in our health care system that have a significant impact on underserved communities,” Garth Graham, vice president of community health and chief.
Healio News 09/22/2020 17:37
According to the Pan American Health Organization, more than 60,000 pregnant women in the Americas have been diagnosed with COVID-19, and 458 have died. Two recent reports published in MMWR underscored the potential for severe outcomes among women with COVID-19. Pregnant women and clinicians should be aware of the risks, including adverse pregnancy outcomes, and ways to prevent infection, said Miranda J. Delahoy, PhD, MSPH, a CDC Epidemic Intelligence Service officer embedded with the National Center for Immunization and Respiratory Diseases. “Identifying COVID-19 during birth.
Healio News 09/22/2020 16:47
COVID-19 outcomes are worse among patients with inflammatory arthritis receiving glucocorticoids, but not in those receiving anticytokine therapy, according to data published in Arthritis & Rheumatology. “The COVID-19 pandemic has brought up new questions for both patients and medical professionals,” Rebecca H. Haberman, MD, MSCI, of the New York University School of Medicine and NYU Langone Orthopedic Hospital, told Healio Rheumatology. “Within the world of rheumatology, one of the most common questions was, ‘What do I do with my medications?’ This was.
Healio News 09/22/2020 16:32
AdventHealth and Rothman Orthopaedic Institute have announced a partnership to establish an orthopedic care network in the central Florida area, according to an AdventHealth Facebook Live stream. The partnership will combine Rothman’s academic and value-based approach to orthopedic care with AdventHealth’s metro Orlando network to create a roster of fellowship trained, subspecialized physicians in the region. “We are proud to be joining together with Rothman Orthopaedic Institute to build an orthopedic program in central Florida that will be a leader in training and education.
Healio News 09/22/2020 15:39
In the early months of the pandemic, a Boston hospital with an infection prevention program that included dedicated COVID-19 units with airborne infection isolation rooms recorded just two cases of nosocomial COVID-19, a study found. Researchers said the results “suggest that overall risk of hospital-acquired COVID-19 was low and that rigorous infection control measures may be associated with minimized risk.” The infection control program at Brigham and Women’s Hospital also included personal protective equipment (PPE) donning and doffing monitors, a universal masking policy,
Healio News 09/22/2020 15:17
In decompensated liver cirrhosis, long-term responders with water retention treated with tolvaptan without recurrence experienced significantly better prognosis, according to study results. “Our data also suggested that obtaining a long-term response without recurrence might be important for achieving a good prognosis,” Masato Nakai, MD, from the department of gastroenterology and hepatology at Hokkaido University Graduate School of Medicine in Japan, said. “In the treatment of decompensated cirrhosis with water retention, the addition of treatments that control inflammation,
Healio News 09/22/2020 14:58
Specific stressors related to the COVID-19 pandemic were linked to rising rates of acute stress and depressive symptoms throughout the United States, according to results of a nationally representative study published in Science Advances. The findings also highlighted the mental health effects of media coverage of the pandemic. “The pandemic is not hitting all communities equally,” E. Alison Holman, PhD, FNP, associate professor at University of California, Irvine’s Sue & Bill Gross School of Nursing, said in a press release. “People have lost wages, jobs and loved.
Healio News 09/22/2020 14:43
Omega-3 polyunsaturated fatty acids appeared to have a small but significant beneficial effect on perinatal depression, according to results of a meta-analysis published in Journal of Clinical Psychiatry. “The absence of recommendations is problematic because omega-3 PUFAs [polyunsaturated fatty acids] are currently widely used during pregnancy and the postpartum period (both to prevent and to treat depressive symptoms), and women ask their health care professionals for advice with regard to safety and effectiveness,” Roel J.T. Mocking, MD, PhD, of the department of psychiatry at.
Healio News 09/22/2020 13:40
Despite dramatic advances in our therapeutic armamentarium for managing psoriasis with pills and biologics, topical therapies remain the most commonly used arrow in our therapeutic quiver. First, 80% of patients with psoriasis have limited body surface area involved and thus are candidates for topical therapy. Second, even our best treatments for patients with moderate to severe psoriasis will fail to achieve 100% clearance in a large percentage of patients. Thus, dermatologists must master both the art and science of the use of topical therapies to manage psoriasis. The American Academy of.
Healio News 09/22/2020 13:40
In approximately one-third of cases, psoriasis begins in pediatric patients, according to the American Academy of Dermatology. Children with psoriasis deal with unique problems such as the treatment and burden of a life-long disease, along with accompanying mental health issues. Healio Psoriatic Disease spoke with A. Yasmine Kirkorian, MD, interim chief of the division of dermatology at Children’s National Hospital and associate professor of dermatology and pediatrics at George Washington University School of Medicine & Health Sciences, about these issues and how clinicians and.
Healio News 09/22/2020 13:17
Although typically a benign finding, right bundle branch block may be associated with increased risk for low exercise tolerance, CVD and death, even in patients with no prior CVD, researchers reported. A review of the Mayo Clinic integrated stress center database for exercise stress tests of 22,806 patients from Minnesota found that individuals with right bundle branch block experienced heightened risk for all-cause mortality, CV death, hypertension, low aerobic capacity, slow heart rate recovery and dyspnea, irrespective of CVD status. “One possible pathophysiological mechanism by which.
Healio News 09/22/2020 13:16
The FDA granted priority review to idecabtagene vicleucel for the treatment of certain adults with relapsed or refractory multiple myeloma, according to the agent’s developers. The designation applies to use of idecabtagene vicleucel (Bristol Myers Squibb, bluebird bio) — often called ide-cel — by patients who have received at least three previous therapies, including an immunomodulatory agent, proteasome inhibitor and anti-CD38 antibody. Ide-cel is an autologous chimeric antigen receptor T-cell therapy that targets the B-cell maturation antigen (BCMA) when it is expressed on.
Healio News 09/22/2020 13:05
Adults with rheumatoid arthritis are 23% more likely to develop type 2 diabetes than individuals without the disease, suggesting that an inflammatory response may drive both conditions, according to findings from a meta-analysis. “Accumulating evidence shows that inflammation emerges as a key factor in the onset and progression of diabetes,” Zixing Tian, a doctoral student in the division of diabetes, endocrinology and gastroenterology at Manchester Academic Health Science Centre, the University of Manchester, United Kingdom, told Healio. “Systemic inflammation associated.
Healio News 09/22/2020 12:50
Earlier this month, phase 3 trials for AstraZeneca’s COVID-19 vaccine candidate were halted due to a suspected serious adverse reaction in a participant from the United Kingdom. The trials have since resumed in the U.K. Healio spoke with Paul A. Offit, MD, director of the Vaccine Education Center at Children’s Hospital of Philadelphia, about the logistics behind stopping and restarting a vaccine trial and what it could mean for attitudes about a COVID-19 vaccine when one is available. – by Caitlyn Stulpin A: Usually the data safety monitoring board and then they report that to.
Healio News 09/22/2020 12:35
Sotorasib demonstrated encouraging anticancer activity among patients with heavily pretreated advanced non-small cell lung cancer who harbor KRAS G12C mutations, according to phase 1 study results presented at ESMO Virtual Congress 2020. “Despite the discovery of the KRAS oncogene almost 4 decades ago, there is no approved therapy targeting this,” David S. Hong, MD, deputy chair of the department of investigational cancer therapeutics at The University of Texas MD Anderson Cancer Center, said during a presentation of the findings, published simultaneously in The New England Journal.
Healio News 09/22/2020 12:30
An analysis from clinical trials and natural history studies showed a statistically significant difference in visual outcomes between Lumevoq-treated patients and untreated patients, according to a press release from GenSight Biologics. In patients with Leber hereditary optic neuropathy, eyes treated with Lumevoq (GS010; lenadogene nolparvovec) showed progressive and sustained improvement from month 12 to month 52, while untreated eyes showed an “absence of recovery” over the same period. The difference became statistically significant at month 18 (P = .01). At month 48, the.
Healio News 09/22/2020 12:12
Patients meet clinical quality targets equally at dialysis facilities that participate vs. centers that do not participate in randomized clinical trials, according to presented research. “The global burden of chronic kidney disease is higher than most chronic diseases,” Kurt Mussina, MBA, said at the American Nephrology Nurses Association National Symposium, adding that the approximately 5% of chronic kidney disease cases that progress to end-stage renal disease “is attributable to almost 1 million deaths each year, and it is the only chronic condition universally covered by.
Healio News 09/22/2020 11:45
Higher fibroscan liver stiffness after hepatitis C antiviral treatment was associated with the development of decompensated cirrhosis, according to study results. “There are many routinely available clinical and laboratory predictors of the development of liver-related complications after anti-viral treatment, including age, a clinical diagnosis of cirrhosis, fibrosis-4 score, model for end-stage liver disease score and viral clearance by sustained virological response,” George N. Iaonnou, MD, MS, of Veterans Affairs Puget Sound Healthcare System, and colleagues wrote. “It is.
Healio News 09/22/2020 11:00
Management of ocular surface disorders may be needed for patients who are on dupilumab to treat atopic dermatitis, according to a presentation at the American Academy of Dermatology virtual meeting. The retrospective chart review included patients who received at least 52 weeks of dupilumab treatment or discontinued before 52 weeks due to ocular surface disorders. Conjunctivitis and conjunctivitis-related symptoms, including red eyes, dry eyes, discharge and blepharitis, were assessed. “Conjunctivitis is an ongoing safety concern associated with dupilumab treatment for AD,” the study.
Healio News 09/22/2020 10:43
The addition of ipatasertib to abiraterone enhanced antitumor activity and improved radiographic PFS as first-line therapy for metastatic castration-resistant prostate cancer, according to data presented at ESMO Virtual Congress 2020. Researchers observed these benefits in the randomized phase 3 IPATential150 study among men whose tumors had PTEN loss. “Metastatic castration-resistant prostate cancer [mCRPC] is a heterogeneous disease, with approximately half of these tumors having lost the AKT phosphatase PTEN, hyperactivating oncogenic PI3K/AKT signaling,” Johann S. de Bono, MD,

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