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Targeted Oncology 12/05/2019 16:55
Although treatment is possible for most types of thyroid cancer, there are few treatment options available once thyroid cancer has progressed, therefore it remains a disease with significant unmet medical needs.
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PubMed News (NIH) 12/04/2019 23:00
Contributors : Irene López-Mateo ; Elvira Alonso-Merino ; Cristian Suárez-Cabrera ; Shue-Ye Cheng ; Susana Alemany ; Jesús M Paramio ; Ana Aranda Series Type : Expression profiling by array Organism : Homo sapiens. Since the thyroid hormone receptor β (TRβ) appears to suppress breast tumor growth and metastasis, we have analyzed the possibility that this receptor could affect cancer stem cell biology using mammospheres from TRβ-expressing MCF-7 cells (MCF7-TRβ cells) treated with the thyroid hormone T3.
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Cancer Network 12/02/2019
Some individuals with sporadic thyroid cancers had a mutation that increased the amount of DUOX2 in the thyroid gland, suggesting that dysregulation of hydrogen peroxide may be the cause of other genetic mutations associated with thyroid cancers, according to the release ...
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JAZF1 Suppresses Papillary Thyroid Carcinoma Cell Proliferation and Facilitates Apoptosis via Regulating TAK1/NF-κB Pathways.
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This application was mainly based on the results of the SELECT Study (Study 303)(1) conducted globally for patients with radioactive iodine-refractory differentiated thyroid cancer.
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ClinicalTrials.gov 11/27/2019 11:40
Standard treatment of thyroid cancer includes thyroidectomy, RAI treatment, and levothyroxine replacement therapy.
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This finding is supported by a review of all known cases of thyroid carcinoma metastasis to the axillary lymph nodes, showing that extensive cervical metastases and/or previous neck dissection may favor lymphatic over hematogenous spread [12.
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Healio News 11/19/2019 14:34
Additionally, select RET inhibitors have shown promise in patients with medullary thyroid cancer who have RET mutations and in those with RET-fusion papillary, poorly differentiated and anaplastic thyroid cancer.
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FeedNavigator (EU) 11/08/2019 12:11
The study showed that the center's Facilitating Anaplastic Thyroid Cancer Specialized Treatment team (FAST) initiative was associated with an increase in survival of anaplastic thyroid cancer at 2 years from 16.5% in a 2000–2013 group of patients — prior to the program's initiation — to 36.5 ...
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Annals of Oncology 11/06/2019 19:00
Abstract. Background. Main challenges in thyroid cancer management are low sensitivity of preoperative differential diagnostics and absence of sufficient prognostic markers for choosing of therapeutic strategy, including decision regarding radioiodine therapy.
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Veracyte endocrinology senior medical director Richard Kloos said: “The findings from these three studies underscore the power of our extensive biorepository of thyroid nodule FNA samples and our optimized RNA sequencing platform to advance understanding of the genomic underpinnings of thyroid cancer and to better capture the biology of thyroid lesions.

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