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PubMed News (NIH) 12/12/2019 23:00
Status Public on Dec 13, 2019 Title Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA Organism Mus musculus Experiment type Expression profiling by high throughput sequencing Summary Mycobacterium tuberculosis’success as a pathogen comes from itsability to ...
European Respiratory Journal 12/12/2019 03:05
Background. As a vulnerable population, children and adolescents with tuberculosis (TB) are faced with many challenges, even those who live in low TB incidence countries. We aimed to evaluate factors associated with TB treatment outcomes allowing more focused interventions to support this population once diagnosed. Methods. A retrospective cohort study using a nationwide surveillance database was performed in children and adolescents (aged 0–18 years) treated for TB in the Netherlands from 1993 to 2018. Logistic regression analyses were used to estimate adjusted odds ratios (aOR) for associated factors of mortality and loss to follow-up (LTFU). Results. Among 3253 eligible patients with known outcomes, 94.4% (95.9% children and 92.8% adolescen.

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