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Your search is now limited to «Leukemia» expert search. 07/19/2019 06:50
Activating mutations in the fms like tyrosine kinase 3 (FLT3) gene are observed in approximately 30% of patients with newly diagnosed acute myeloid leukemia (AML.
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PubMed News (NIH) 07/19/2019
Gene expression and mutation analysis of both mouse models and primary human leukemia suggested that these factors form a functional gene regulatory network targeted by multiple mutations in human B-ALL.
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PR Newswire 07/18/2019 08:30
The American Cancer Society's estimates for leukemia in the United States , for 2019, indicates that approximately 61,780 new cases of leukemia and 22,840 deaths from leukemia are expected to occur in the country.
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GlobeNewswire 07/17/2019 16:01
MacroGenics Provides Update on Flotetuzumab Program in Acute Myeloid Leukemia Nasdaq:MGNX.
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LB100 does not sensitize CML stem cells to tyrosine kinase inhibitor–induced apoptosis.
More from Science Translational Medicine: 07/17/2019 08:21
Global Blood Cancer Drugs Market report is first of its kind research report that incorporates the overview, summary, market dynamics, competitive analysis, and leading player’s various strategies to sustain in the worldwide market.
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CNN (United States) 07/16/2019 20:25
Dana Hunsinger Benbow of the Indianapolis Star reported the news, noting Moore—who played volleyball at Linton-Stockton High in Indiana—was diagnosed with acute myeloid leukemia in January 2018.
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Orphan designation: Recombinant chimeric monoclonal antibody against CD20, Treatment of chronic lymphocytic leukaemia, 26/11/2009, Positive.
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Technology Org 07/16/2019 01:50
New study discovers genetic changes linked to leukaemia in children with Down’s syndrome.
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Among 5 MRD+ patients, there was a demonstrable antileukemic effect of the TAA-CTLs alone without any concomitant chemotherapy in 2 patients, as demonstrated by the negative of MRD in bone marrow after TAA-CTL infusion.
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Stem cells are taken from a donor's blood sample so are preferable to bone marrow transplants, which have to be done under general anaesthetic.
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Purpose:. The anti-CCR4 mAb, mogamulizumab, offers therapeutic benefit to patients with adult T-cell leukemia-lymphoma (ATL), but skin-related adverse events (AE) such as erythema multiforme occur frequently. The purpose of this study was to determine the mechanisms by which mogamulizumab causes skin-related AEs in patients with ATL. Experimental Design:. We investigated whether autoantibodies were present in patients’ sera using flow cytometry to determine binding to keratinocytes and melanocytes ( n = 17), and immunofluorescence analysis of tissue sections. We analyzed the IgM heavy chain repertoire in peripheral blood mononuclear cells before and after mogamulizumab or other chemotherapy by next-generation sequencing (NGS; n = 16). Results.
More from Clinical Cancer Research - Recent Issues (abstracts): 07/14/2019 18:17
Therefore, while the relationship between childhood brain tumors and cured meats is well-established, its relationship to leukemia has not been explored as much.
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