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News-Medical.net 09/17/2019 02:51
So, as a first step, the researchers tested their system on biopsies taken from ovarian peritoneal metastases and the healthy peritoneum of women undergoing laparoscopy and surgery for ovarian cancer.
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Gemcitabine-loaded RGD modified liposome for ovarian cancer: preparation, characterization and pharmacodynamic studies.
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Medical Xpress - Cancer News 09/16/2019 09:24
Most cases of ovarian cancer occur in women who have already gone through menopause, and more than half the cases of ovarian cancer diagnosed are women over 65 years old.
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ClinicalTrials.gov 09/16/2019 07:44
Condition : BRCA Wild Type Platinum Sensitive Recurrent Ovarian Cancer Intervention : Drug: Olaparib tablets Sponsor : National Cancer Institute, Naples Recruiting.
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Generally, though, the strongest risk factors for ovarian cancer (like having family members with ovarian or breast cancer, or having no children) are not things women are likely to be able to change,” the researcher added.
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Cancer Network 09/16/2019
How much do you know about the role of long non-coding RNAs in ovarian cancer? Now is your chance to find out.
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The addition of ovarian function suppression (OFS) for 5 years to tamoxifen (TAM) for treatment of premenopausal patients with breast cancer after completion of chemotherapy has beneficial effects on disease-free survival (DFS.
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Channel NewsAsia (Singapore) 09/13/2019 15:41
The study also found that the link between PTSD and ovarian cancer persisted for the most aggressive forms of ovarian cancer.
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A new study, from the University of Colorado School of Medicine, has found that, with both the hormonal and non-hormonal IUD, women can lower their cancer risk by up to 32% (file image) Ovarian cancer occurs when the disease originates from the cells in and around the ovary.
More from Mail on Sunday (United Kingdom):
Chemoresistance is driven by unique regulatory networks in the genome that are distinct from those necessary for cancer development. Here, we investigate the contribution of enhancer elements to cisplatin resistance in ovarian cancers. Epigenome profiling of multiple cellular models of chemoresistance identified unique sets of distal enhancers, super-enhancers (SE), and their gene targets that coordinate and maintain the transcriptional program of the platinum-resistant state in ovarian cancer. Pharmacologic inhibition of distal enhancers through small-molecule epigenetic inhibitors suppressed the expression of their target genes and restored cisplatin sensitivity in vitro and in vivo. In addition to known drivers of chemoresistance, our fi.
More from Cancer Research - Recent Issues (abstracts):
Purpose:. STM 434 is a soluble receptor ligand trap targeting activin A, a protein in the TGFβ family that plays important roles in growth, differentiation, and cancer cachexia. This study evaluated the safety, antitumor activity, and metabolic effects of STM 434 in a first-in-human, multicenter, phase I clinical trial (NCT02262455). Patients and Methods:. Patients with advanced solid tumors were enrolled in 8 dose cohorts ranging from 0.25 mg/kg every 4 weeks to 8 mg/kg every 2 weeks via a 3 + 3 dose-escalation design. The primary endpoint was maximum tolerated dose (MTD). Secondary endpoints included safety, pharmacokinetics, and response. As activin A is implicated in metabolism and muscle function, changes in key metabolic parameters, inc.
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Healio News 09/12/2019 13:24
PTSD may increase risk for ovarian cancer Symptoms of PTSD appeared associated with increased risk for ovarian cancer, especially among premenopausal women, according to study results published in Cancer Research.
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DoctorsLounge 09/12/2019 13:00
Given the grave nature of an advanced ovarian cancer diagnosis, even a modest increase in the use of IUDs may lead to a decrease in incidence in ovarian cancer in a general population of women, leading to a significant population-level effect," the authors ...
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Business Wire 09/12/2019 04:00
The accepted abstracts summarize clinical trials in which Rubraca is being evaluated as a single agent in advanced ovarian and prostate cancers.
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Technology Org 09/09/2019 15:30
The collaborative study, led by Schlaepfer and Stupack, focused on high-grade serous ovarian carcinoma, a subtype of epithelial cancer that starts in the outer surface of the ovaries or fallopian tubes.
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ETHealthWorld (India) 09/07/2019 05:51
The study published in the journal Cancer Research , also found that the link between PTSD and ovarian cancer remained for the most aggressive forms of ovarian cancer.
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PubMed News (NIH) 09/06/2019
Contributors : Heejung An ; So-hyun Hwang ; Ju-Yeon Jeong ; Hyun Park Series Type : Non-coding RNA profiling by array Organism : Homo sapiens. Cancer stem cells can self-renew, proliferate into differentiated cells, or enter a quiescent state and are regarded to cause chemoresistance and recurrence.
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