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PubMed News (NIH) 08/14/2020
Contributors : A Ndoja ; R Reja Series Type : Genome binding/occupancy profiling by high throughput sequencing Organism : Mus musculus. The realization in the last decade that dysregulated microglia are intimately involved in Alzheimer’s disease (AD) pathogenesis has been a major advance.
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FeedNavigator (EU) 08/13/2020 10:53
Energy demand of neurons in brain that is covered by glucose supply from the blood is ensured by glucose transporters in capillaries and brain cells. In br.
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NaturalNews.com 08/12/2020 13:13
The Alzheimer’s group also had more pro-inflammatory bacteria in their gut.
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Alzheimers News Today 08/12/2020 10:30
XPro1595, an investigational therapy by INmune Bio, can lower brain inflammation in people with mild to moderate Alzheimer’s disease, according to interim results of a clinical trial. Specifically, the Phase 1b clinical trial (NCT03943264) shows evidence that XPro1595 decreases white matter free water, a biomarker of neuroinflammation measured by magnetic resonance imaging (MRI). XPro1595 was […]. .
A team at the CRCHUM—Université de Montréal's hospital research center—has discovered a new function for proteins responsible for DNA repair in the control of an inflammatory response in aging cells, also known as senescent cells, which accumulate over time.
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Medical Xpress 08/10/2020 09:10
Yet long-lasting changes in the brain after illness are also closely linked to increased risk for age-related cognitive decline and Alzheimer's disease.
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Seeking Alpha 08/09/2020 05:30
Preliminary data reported in 6 patients demonstrated that XPro decreases white matter free water, a biomarker of neuro-inflammation that is measured by MRI in patients with Alzheimer's disease.
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Alzforum News 08/08/2020 16:45
Interestingly, frail people had levels of microglial activation on par with people who had had AD dementia, casting inflammation as a unifying factor across different types of cognitive impairment.
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Medindia.com 08/06/2020 08:56
An increase in body weight is associated with a decrease in brain activity and blood flow. The changes can be virtually assessed by neuroimaging in brain regions, including those influenced by Alzheimer's disease pathology such as the hippocampus.
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