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PubMed News (NIH) 08/14/2020
Contributors : A Ndoja ; R Reja Series Type : Genome binding/occupancy profiling by high throughput sequencing Organism : Mus musculus. The realization in the last decade that dysregulated microglia are intimately involved in Alzheimer’s disease (AD) pathogenesis has been a major advance.
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FeedNavigator (EU) 08/13/2020 10:53
Energy demand of neurons in brain that is covered by glucose supply from the blood is ensured by glucose transporters in capillaries and brain cells. In br.
More from FeedNavigator (EU): 08/12/2020 13:13
The Alzheimer’s group also had more pro-inflammatory bacteria in their gut.
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Alzheimers News Today 08/12/2020 10:30
XPro1595, an investigational therapy by INmune Bio, can lower brain inflammation in people with mild to moderate Alzheimer’s disease, according to interim results of a clinical trial. Specifically, the Phase 1b clinical trial (NCT03943264) shows evidence that XPro1595 decreases white matter free water, a biomarker of neuroinflammation measured by magnetic resonance imaging (MRI). XPro1595 was […]. .
A team at the CRCHUM—Université de Montréal's hospital research center—has discovered a new function for proteins responsible for DNA repair in the control of an inflammatory response in aging cells, also known as senescent cells, which accumulate over time.
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Medical Xpress 08/10/2020 09:10
Yet long-lasting changes in the brain after illness are also closely linked to increased risk for age-related cognitive decline and Alzheimer's disease.
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Seeking Alpha 08/09/2020 05:30
Preliminary data reported in 6 patients demonstrated that XPro decreases white matter free water, a biomarker of neuro-inflammation that is measured by MRI in patients with Alzheimer's disease.
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Alzforum News 08/08/2020 16:45
Interestingly, frail people had levels of microglial activation on par with people who had had AD dementia, casting inflammation as a unifying factor across different types of cognitive impairment.
More from Alzforum News: 08/06/2020 08:56
An increase in body weight is associated with a decrease in brain activity and blood flow. The changes can be virtually assessed by neuroimaging in brain regions, including those influenced by Alzheimer's disease pathology such as the hippocampus.
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