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NASDAQ 02/27/2020 17:03
(RTTNews) - Biogen Inc. (BIIB) and Sangamo Therapeutics Inc. (SGMO), Thursday announced that they have reached a global collaboration deal to develop gene regulation therapies for Alzheimer's, Parkinson's, neuromuscular, and other neurological diseases.
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STAT 02/27/2020 16:58
The drug maker Biogen announced late Thursday that it would license two preclinical drugs from Sangamo Therapeutics, both of which use a genome-editing technology called zinc fingers to regulate the expression of genes involved with neurological diseases like Alzheimer’s and Parkinson’s.
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Business Wire 02/27/2020 16:06
CAMBRIDGE, Mass. & BRISBANE, Calif.--(BUSINESS WIRE)--Biogen Inc. (Nasdaq: BIIB) and Sangamo Therapeutics, Inc. (Nasdaq: SGMO), a genomic medicine company, today announced that they have executed a global licensing collaboration agreement to develop and commercialize ST-501 for tauopathies including Alzheimer’s disease, ST-502 for synucleinopathies including Parkinson’s disease, a third undisclosed neuromuscular disease target, and up to nine additional undisclosed neurological disease targets.
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Evidence from animal models has found that changes to regulation of the PSEN1 gene is associated with Alzheimer's-like pathology, but only a handful of studies have investigated DNA modification of the gene in humans.
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Becker's Hospital Review 02/27/2020 12:29
Health2047, the American Medical Association's innovation enterprise, announced on Feb. 27 its fourth spinout company: Medcurio, which develops software to improve healthcare organizations' data access and usage.
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Alzforum News 02/26/2020 16:37
At the HAI 2020 conference, the tracers PI-2620 and APN-1607 appeared to bind frontotemporal dementia tau. MK-6240 looked highly sensitive. And JNJ-067 and SNFT-1 are two new kids in town.
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News-Medical.net 02/26/2020 13:07
A recent study published in Nature has reported two conserved epigenetic regulators as novel anti-aging targets.
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Rapidly Progressing Neurocognitive Disorder in a Male with FXTAS and Alzheimer's Disease Elber Yuksel Aydin,1,2 Andrea Schneider,1,3 Dragana Protic,1,4 Jun Yi Wang,1,5 Veronica Martínez-Cerdeño,1,6 Flora Tassone,1,7 Hiu-Tung Tang,7 Susan Perlman,8 Randi J Hagerman1,3 1Medical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California Davis, Sacramento, CA, USA; 2Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey; 3Department of Pediatrics, University of California Davis School of Medicine, Sacramento, CA, USA; 4Department of Pharmacology, Clinical Pharmacology and Toxicology, School of Medicine, University of Belgrade, Belgrade, Serbia; 5Center for Mind and Brain, University of California Davis.
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GlobeNewswire 02/24/2020 08:30
The Company’s product candidates are supported by biomarkers and target genetically defined patient populations in frontotemporal dementia and Alzheimer’s disease.
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Fight Aging! 02/23/2020 09:55
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/ Contents Request for Startups in the Rejuvenation Biotechnology Space, 2020 Edition Activating
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FeedNavigator (EU) 02/21/2020 14:11
Int J Mol Sci. 2020 Feb 14;21(4). pii: E1289. doi: 10.3390/ijms21041289.
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