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FeedNavigator (EU) 10/23/2019 02:37
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Cardiac Rhythm News 10/22/2019 11:19
A press release from AstraZeneca outlines that the approval is based on results from the DECLARE-TIMI 58 CV outcomes trial (CVOT), which it describes as the largest sodium-glucose cotransporter 2 (SGLT2) inhibitor CVOT conducted to date to evaluate type 2 diabetes patients with multiple CV risk factors or established CV disease.
PR Newswire 10/22/2019 10:00
SHENZHEN, China and ROCKVILLE, Md., Oct. 22, 2019 /PRNewswire/ -- HighTide Therapeutics Inc. ("HighTide"), a clinical-stage biopharmaceutical company, today announced that the last patient has been enrolled in A Proof-of-Concept and Dose-Ranging Study Investigating the Efficacy and Safety...
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ClinicalTrials.gov 10/22/2019 08:02
The goal of this clinical trial is to evaluate the effect of low doses of linagliptin + metformin vs metformin alone on physiopathological parameters, such as glucose metabolism, insulin resistance, insulin secretion and pancreatic beta cell function in patients with impaired fasting ...
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In August this year, the European Commission has approved an update to the marketing authorisation for Forxiga to include positive cardiovascular (CV) outcomes and renal data based on phase III DECLARE-TIMI 58 trial in adults with T2D.
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American Diabetes Journals 10/21/2019 15:00
GRADE in the Context of Other Major Diabetes Studies GRADE fits into a spectrum of large trials of patients with T2DM evaluating durability of glycemic therapy (Table 2.
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ETHealthWorld (India) 10/21/2019 03:07
The approval by the U.S. Food and Drug Administration is based on results from the DECLARE-TIMI 58 clinical trial, the British drugmaker said and follows a similar approval by the European authorities in August.
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Drugs.com 10/20/2019 22:10
The Phase III DECLARE-TIMI 58 trial confirmed the well-established safety profile of Farxiga.
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In addition, for applications involving clinical trials: A proposed Clinical Trial application may include study design, methods, and intervention that are not by themselves innovative but address important questions or unmet needs.
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GlobeNewswire 10/16/2019 09:00
PharmaCyte’s therapy for Type 1 diabetes and insulin-dependent Type 2 diabetes involves encapsulating a human cell line that has been genetically engineered to produce and release insulin in response to the levels of blood sugar in the human body.
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Diabetes In Control News 10/14/2019 20:07
Recent cardiovascular outcomes trials such as LEADER and SUSTAIN-6 have provided evidence to support the American Diabetes Association’s decision to recommend GLP-1 receptor agonists as well as SGLT2 inhibitors for diabetes patients with high risk for ASCVD.
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Business Wire 10/14/2019 09:00
PharmaCyte’s therapy for Type 1 diabetes and insulin-dependent Type 2 diabetes involves encapsulating a human cell line that has been genetically engineered to produce and release insulin in response to the levels of blood sugar in the human body.
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Benzinga 10/11/2019 19:26
Eight leading retinal centers across the United States are participating in the OPTIC phase 1 trial for ADVM-022.
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