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FeedNavigator (EU) 05/02/2020 03:47
The aggregation of proteins in amyloid structures, a process described in mammals and fungus and bacteria, is implied in approximately 36 human diseases, including Alzheimer’s disease, Parkinson’s disease and type 2 diabetes.
FeedNavigator (EU) 04/09/2020 10:07
Dietary supplementation with curcumin has been previously reported to have beneficial effects in people with insulin resistance, type 2 diabetes (T2D) and Alzheimer’s disease (AD). This study investigated the effects of dietary supplementation with curcumin on key peptides implicated in insulin resistance in individuals with high risk of developing T2D. Plasma samples from participants recruited for a randomised controlled trial with curcumin (180 mg/day) for 12 weeks were analysed for circulating glycogen synthase kinase-3 β (GSK-3β) and islet amyloid polypeptide (IAPP). Outcome measures were determined using ELISA kits. The homeostasis model for assessment of insulin resistance (HOMA-IR) was measured as parameters of glycaemic control. Cu.

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