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PubMed News (NIH) 08/07/2020
Contributors : Ujué Fresán ; Maria Rodríguez-Sánchez ; Oscar Reina ; M L Espinàs Series Type : Genome binding/occupancy profiling by high throughput sequencing Organism : Drosophila melanogaster. Drosophila Haspin kinase phosphorylates Histone H3 at threonine 3 at centromeric heterochromatin and either lamin- or polycomb-enriched euchromatic regions, being required for nuclear organization of interphase cells and polycomb-dependent gene silencing.
PubMed News (NIH) 08/06/2020
Contributors : Atsushi Suzuki ; Yasuyuki Ohkawa ; Masao Nagasaki ; Kenichi Horisawa ; Kazuko Ueno Series Type : Genome binding/occupancy profiling by high throughput sequencing Organism : Mus musculus. We have found three specific combinations of two transcription factors, comprising Hnf4alpha plus Foxa1, Foxa2, or Foxa3, could convert mouse embryonic fibroblasts (MEFs) into cells that closely resemble hepatocytes (iHep cells) in vitro.
Scientific American 08/05/2020 07:30
Last week an official at the Plant Protection and Quarantine program at the USDA’s Animal and Plant Health Inspection Service (APHIS) said that so far the agency has “identified 14 different species of seeds, including mustard, cabbage, morning glory and some of the herbs—like mint, sage, rosemary, lavender—and other seeds, like hibiscus and roses.
PubMed News (NIH) 08/04/2020
Contributors : Yahya Benslimane ; Thierry Bertomeu ; Jasmin Coulombe-Huntington ; Mary McQuaid ; María Sánchez-Osuna ; David Papadopoli ; Daina Avizonis ; Mariana S Russo ; Caroline Huard ; Ivan Topisirovic ; Hugo Wurtele ; Mike Tyers ; Lea Harrington Series Type : Other Organism : Homo sapiens. Using genome-wide CRISPR-Cas9 screens and other cell-based assays, we show that the pro-longevity agent resveratrol and its analogue pterostilbene induce a genetic signature of replicative stress that is similar to hydroxyurea.

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