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FeedNavigator (EU) 04/24/2020 07:37
Background: We hypothesized that the change in stroke risk profile between baseline and follow-up may be a better predictor of ischemic stroke than the baseline stroke risk determination using the CHA2DS2-VASc score ((congestive heart failure, hypertension, age ≥75 years (doubled), diabetes, stroke/transient ischemic attack/thromboembolism (doubled), vascular disease (prior myocardial infarction, peripheral artery disease, or aortic plaque), age 65–75 years, sex category (female))).
FeedNavigator (EU) 04/22/2020 07:29
The present study reported a subset of circulating immunoglobulin G autoantibodies (IgGs) from patients with T2DM with AF (T2DM/AF)-induced intracellular calcium elevation in both human induced pluripotent stem cell (iPSC)-derived and mouse atrial cardiomyocytes, whereas (identical concentrations of) IgGs from patients with T2DM without AF could not.
FeedNavigator (EU) 03/30/2020 10:37
A total of 7020 patients were treated, and the trial continued until ≥691 patients experienced the primary endpoint of three‐point major adverse cardiovascular events (3P‐MACE.
FeedNavigator (EU) 03/26/2020 09:20
Common predisposing factors of HF include hypertension, valvular heart disease, diabetes, atrial fibrillation (AF), coronary artery disease (CAD) and alcohol consumption.2–4 Currently, the latest evidence-based medical treatment for HF has markedly improved the survival rate, major adverse cardiovascular events (MACE) and re-hospitalisation ...

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