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PubMed News (NIH) 12/14/2019 23:00
Contributors : Clifton L Dalgard ; Andrew L Snow Series Type : Expression profiling by high throughput sequencing Organism : Homo sapiens. Transcriptome profiling and functional analyses on expanding Tcons revealed that FOXP3 enhances expression of the SLAM family receptor CD48, which in turn sustains basal autophagy and suppresses pro-apoptotic p53 signaling.
PubMed News (NIH) 12/14/2019 23:00
Contributors : Xiuye Wang ; Elmira Forouzmand ; Yongsheng Shi Series Type : Expression profiling by high throughput sequencing ; Other Organism : Homo sapiens. Infection by viruses, including Herpes Simplex virus-1 (HSV-1), and cellular stresses cause widespread disruption of transcription termination (DoTT) of RNA polymerase II (RNAPII).
PubMed News (NIH) 12/14/2019 23:00
Contributors : Kamin J Johnson ; Robert A Budinsky ; Shreedharan Sriram Series Type : Expression profiling by high throughput sequencing Organism : Rattus norvegicus. We report the RNAseq-based transcriptome profiles of rat gestation day 20 dam liver, fetal male and female liver, fetal male pituitary, and fetal testis following in utero exposure to either 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) or 2,3,7,8-tetrachlorodibenzofuran (TCDF).
PubMed News (NIH) 12/14/2019 23:00
Contributor : Nathan G Walworth Series Type : Methylation profiling by high throughput sequencing Organism : Trichodesmium erythraeum IMS101. We present population-level epigenetic variation in Trichodesmium erythraeum IMS101 associated with steady-state Fe-limitation at two different P concentrations on both short (i.e.
PubMed News (NIH) 12/14/2019 23:00
Contributors : Ilya M Flyamer ; Shelagh Boyle ; Iain Williamson ; Dipta Sengupta ; Wendy A Bickmore ; Robert S Illingworth Series Type : Other Organism : Mus musculus. 1. Loss of RING1B substantially disrupts nuclear architecture. 2. PRC1 mediated looping can occur at a Mb scale and is independent of CTCF. 3. Polycomb mediated looping is driven by canonical PRC1 complexes. 4. Trimeric PRC1-mediated interactions occur in vitro and in vivo. 5. Gene up-regulation does not directly lead to the loss of PRC1 loops.
PubMed News (NIH) 12/13/2019 23:00
Contributors : Joshua J Faber-Hammond ; Gabe Preisling Series Type : Genome variation profiling by genome tiling array Organism : Haplochromis burtoni ; Maylandia zebra ; Neolamprologus brichardi ; Oreochromis niloticus ; Pundamilia nyererei. This study examines genomic copy-number variation between two African cichlid species through array comparative genomic hybridization.
PubMed News (NIH) 12/13/2019 23:00
Contributors : Noémie Vimont ; Sandra Cortijo ; Bénédicte Wenden ; Philip A Wigge ; Fu X Quah Series Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencing Organism : Prunus avium. Chromatin immunoprecipitation-sequencing (ChIP-seq) is a robust technique to study interactions between proteins, such as histones or transcription factors, and DNA.
PubMed News (NIH) 12/13/2019 23:00
Contributors : Kenji Nanishi ; Katsutoshi Shoda ; Tomohiro Arita ; Hirotaka Konishi ; Eigo Otsuji Series Type : Non-coding RNA profiling by array Organism : Homo sapiens. By the high sensitive cricular RNA micro array, we commpared 10211 circular RNAs abundant in the human gastric cancer tissues and adjacent normal gastric mucosa tissues, and the functional role of differentially expressed circular RNAs were analyzed by bioinformatics.

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