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We hypothesized that overexpression of Aurora A was associated with poor survival in obesity breast cancer and the related axis mechanism was involved.
More from International Journal of COPD: 06/02/2020 07:08
Conditions : p16INK4a Negative Oropharyngeal Squamous Cell Carcinoma; Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7; Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7; Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7; Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7; Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7; Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7; Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7; Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7; Stage IVA Hypopharyngeal Squamous Cell Carcinoma AJCC v7; Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7; Stage IVA Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7; Stage IVA Oropharyngeal Squamous Cell Carcin.
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Background: Lung cancer is the number one cause of cancer-related death, and lung adenocarcinoma (LUAD) is the most frequent type. Lung screening with computed tomography has allowed detection of early nodules that need diagnostic definition. We have identified the sodium-dependent glucose transporter 2 (SGLT2) as a novel diagnostic and therapeutic target that may aid the identification and the treatment of early LUAD. However, a limitation of these studies is the lack of experimental models of early cancer. Patient-derived xenografts (PDXs) are a reliable tool of translational oncology. However, the establishment of PDXs from early-stage, low-grade LUAD is characterized by low efficiency and extremely long experimental times. To study the
More from Cancer Research - Recent Issues (abstracts):
RNA-Seq Blog 06/02/2020
Tempus, a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare, announced the launch of two new oncology tests designed to equip physicians with even more precise genomic data in an effort to improve therapeutic outcomes.
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PubMed News (NIH) 06/02/2020
Developing LMP1-driven B-cell lymphomas were transplanted in secondary Rag2KOcgKO or Rag2KO mice.
More from PubMed News (NIH): 06/01/2020 23:55
A team of researchers at The Institute of Cancer Research (ICR) in London found that the test can detect traces of cancer DNA in the bloodstream.
More from 06/01/2020 05:25
Researchers believe that genetic screening could detect potentially aggressive cancers more effectively than PSA testing - which is controversial because of its high rates of over-diagnosis.
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Purpose:. Prostate cancers with mutations in genes involved in homologous recombination (HR), most commonly BRCA2, respond favorably to PARP inhibition and platinum-based chemotherapy. We investigated whether other prostate tumors that do not harbor deleterious mutations in these particular genes can similarly be deficient in HR, likely rendering those sensitive to HR-directed therapies. Experimental Design:. Homologous recombination deficiency (HRD) levels can be estimated using various mutational signatures derived from next-generation sequencing data. We used this approach on whole-genome sequencing (WGS; n = 311) and whole-exome sequencing (WES) data ( n = 498) of both primary and metastatic prostate adenocarcinomas to determine whether p.
More from Clinical Cancer Research - Recent Issues (abstracts):
To improve testing rates, a return of germline results program for patients enrolled in the Total Cancer Care (TCC) protocol at Markey Cancer Center (MCC) was initiated.
More from Cancer Epidemiology, Biomarkers & Prevention Recent Issues (abstracts):
STAT 05/30/2020 07:00
Covid-19 news could be nudged out of the spotlight this weekend as the American Society of Clinical Oncology’s annual scientific meeting, this year being held virtually, mobilizes 40,000 people around the world across industry, academia, and government.
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FeedNavigator (EU) 05/30/2020 00:12
16869 patients who had initial cancer diagnosis after T2DM were matched with 83046 patients without cancer (controls) using a matching ratio up to one‐to‐five propensity score‐matching method.
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Multiple logistic regression examined the association of HPV with clinical features and other risk factors, using SPSS® software.
More from International Journal of Paediatric Dentistry (EU):
Becker's Hospital Review 05/29/2020 13:02
Researchers gathered data from the COVID-19 and Cancer Consortium database on patients with active cancer or previous cancer diagnoses who were also diagnosed with COVID-19.
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Business Wire 05/29/2020 12:35
In a completely novel concept, the test analyzed the patient’s immune response to the presence of cancer by isolating stromal cells originating from cancer sites that have migrated into the blood stream.
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Benzinga 05/29/2020 09:00
For cancers where a treatment path is not clear, such as many metastatic and recurrent cancers, the PARIS test provides crucial information to the treating physicians to match the right drug to the right patient.
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