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Using an array of receptors to sense neurons in peril, microglia make matters worse by taking bites out of the struggling cells.
More from Alzheimer's Research & Therapy: 07/18/2019 02:50
The drug, called COR388, inhibits the bacterial toxins and reduces the levels of inflammatory biomarkers like RANTES and ApoE protein, in the blood and cerebrospinal fluid of people with AD.
More from 07/18/2019 01:15
Eisai presented data on biomarkers of neurodegeneration (cerebral spinal fluid, or CSF, biomarkers), which suggested that treatment with BAN2401 in patients with early Alzheimer's disease was associated with reduced neurodegeneration at both 12- and 18-months timepoints.
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In addition, this FOA encourages research that would identify new biomarkers that could serve as surrogate measures for disease progression in AD/ADRD.
More from National Institutes of Health (NIH):
Benzinga 07/17/2019 16:05
The Company's product candidates are supported by biomarkers and target genetically defined patient populations in frontotemporal dementia and Alzheimer's disease.
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PR Newswire 07/17/2019 15:22
Other new data presented at the conference included: Advances in emerging blood biomarkers that may support early detection, improved diagnosis and enhanced clinical trial recruitment for Alzheimer's and other dementias, and other neurodegenerative diseases.
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GlobeNewswire 07/17/2019 11:45
NEW YORK, July 17, 2019 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. ("Anavex" or the "Company") (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases including Alzheimer’s disease, Parkinson’s disease, Rett syndrome and other central nervous system (CNS) diseases, today reported results from a study evaluating the gut microbiota of patients in the ongoing ANAVEX ® 2-73 Phase 2a extension study of ANAVEX ® 2-73, a selective sigma-1 receptor agonist.
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Bio-Medicine.Org 07/17/2019 03:22
BALTIMORE (PRWEB) July 17, 2019 As part of continuing efforts to provide patients with the latest in medical technology, Mercy Medical Center has added the Medtronic O-arm® Mobile Surgical Imaging System to lessen radiation exposure and improve spinal surgery results, Charles C. Park,...
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EurekAlert 07/17/2019
This multicenter study used in vivo β-amyloid cerebrospinal fluid, a biomarker of Alzheimer disease, and positron emission tomography findings to track progression of Alzheimer disease over six years among study participants.
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This population-based cohort study estimates the sex- and age-specific prevalence of 3 imaging biomarker–based definitions of the Alzheimer disease spectrum from the National Institute on Aging–Alzheimer’s Association research framework and compares these entities with clinically defined diagnostic entities commonly linked with Alzheimer disease.
More from Archives of Neurology - Abstracts:
Psychologists at the University of California, Berkeley discovered a link between insufficient sleep and the presence of beta-amyloid protein in their brains — a biomarker associated with the development of Alzheimer’s.
More from PsyCentral - World of Psychology:

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