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Next Avenue 01/22/2019 08:00
We hear a lot in the news and from the many health and aging advocacy organizations about how we can live better and longer lives if we take good care of ourselves. There are so many aspects to self care, including nutrition, fitness, mental health and medical care. Here are six books from 2018 that…. The post 6 Great Health Books to Read This Year appeared first on Next Avenue .
Genetic Literacy Project 01/22/2019 07:02
The study also found that a variant of a gene called APOE4, which confers a high risk of Alzheimer’s in whites, seemed to be less of a peril for African–Americans.
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Fight Aging! 01/22/2019 06:22
As is the case for other neurodegenerative conditions, Alzheimer's disease has a strong inflammatory component. Even if other mechanisms are important, and there is very strong evidence for this to be the case, dysregulation of immune cells in the brain contributes notably to the progression of the condition. As recent work demonstrates, this dysregulation may arise in large degree because of the inflammatory signaling generated by senescent cells, but these errant cells are are not the only way in which the aged, damaged immune system can become more inflamed and thus more hostile towards the tissues it is supposed to help maintain. Inflammation for short periods of time is a necessary part of the immune response, and assists in the remova.
More from Fight Aging!: 01/22/2019 01:39
A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease - even before they show signs of confusion and memory loss.
More from 01/21/2019 18:14
In a study of 247 people with a genetic mutation known to trigger young-onset Alzheimer's, tests revealed higher than normal levels of a specific protein that rose over.
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Led by Washington University, the aim of DIAN is to identify potential biomarkers of Alzheimer's in people who carry a gene mutation that causes the disease.
More from Mail on Sunday (United Kingdom): 01/21/2019 11:34
The team assessed more than 400 participants included in the Dominantly Inherited Alzheimer's Network (DIAN), each of whom had rare genetic variants running in their families that typically cause Alzheimer’s to develop in the 30s, 40s, or 50s.
More from 01/21/2019 10:00
Participants in DIAN carry one of the gene mutations (APP, PSEN1, PSEN2) known to cause dominantly inherited Alzheimer's disease.
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PubMed News (NIH) 01/18/2019 23:00
Contributors : Song Yang ; Jie Luo Series Type : Expression profiling by high throughput sequencing Organism : Cyprinus carpio. purpose?To elucidate the relationship of utilization different type of diets in fish method?enzyme activity determination and transcriptome sequencing were performed in common carp fed with single animal diet group (group AD), plant diet group (group PD) and mix diets group (group MD).
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BioNewsFeeds 01/18/2019 10:00
The presence of ApoE4, a specific form of the ApoE gene, is associated with a higher risk of developing Alzheimer’s.
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Healio News 01/18/2019 05:30
Splashy headlines in the mainstream media that proclaim advances in medicine are often not what they seem. That may be the case with a recent series of FDA approvals surrounding the direct-to-consumer genetic testing platform, 23andMe. A 2017 approval for the product to detect mutations associated with a cross-section of 10 diseases, followed by last year’s approval to detect variants in the cancer-associated BRCA pathway, has pundits speculating whether such technology will be approved to predict risk for other conditions, including those that fall under the rheumatology umbrella. While.
FierceMedicalDevices 01/17/2019 08:04
Undeterred, Alzheon reckoned it could resurrect the program by targeting a subgroup of patients with two copies of the APOE4 gene, a group that accounts for about 10% of Alzheimer’s patients.
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ENDPOINTS 01/17/2019 07:09
Under that plan, formulated based on a post doc analysis, Alzheon would only need to recruit 500 patients each for its two Phase III trials, focusing on a genetically-defined AD population of APOE4/4 homozygotes.
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