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BIOENGINEER.ORG 02/24/2020 15:40
Previous studies in Dr. Fossati’s Lab showed that these drugs were effective in cell and animal models at targeting certain features of Alzheimer’s disease, including mitochondrial dysfunction, amyloid protein build-up, and inflammation.
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Stem Cells Portal 02/24/2020 11:17
RIO DE JANEIRO (BR), February 2020 — Astrocytes are neural cells with many important functions in the nervous system. The inflammation of these cells occurs in brain infections and neurodegenerative disorders, a process called astrogliosis. Aware of this fundamental process for the prevention of diseases and improvement of current treatments, a team led by researchers at the D'Or Institute for Research and Education (IDOR) and other five Brazilian Federal Universities published one of the first studies to categorically observe this inflammatory reaction in human astrocytes created in the laboratory. Astrogliosis is an inflammatory process common to several diseases such as Parkinson's, Alzheimer's, multiple sclerosis and congenital malforma.
PR Newswire 02/24/2020 08:17
Dr. Akassoglou and colleagues discovered that fibrin, a blood-clotting factor, is implicated in the toxic inflammation that activates the brain's immune response and damages neurons in neurological diseases including Alzheimer's disease (AD) and multiple sclerosis (MS) as well as in a variety of peripheral indications where destructive inflammation plays a role in the disease process ...
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LocalTechWire 02/21/2020 12:03
HIGH POINT — vTv Therapeutics, a clinical-stage biopharmaceutical company that is developing a pipeline of clinical drug candidates for the treatment of Alzheimer’s disease, diabetes, and inflammatory disorders, on Thursday reported a loss of $4.4 million in its fourth quarter.
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Forbes 02/21/2020 06:30
Biotechnology startup Eleusis is exploring sub-perceptual levels of LSD as a potential treatment for Alzheimer's disease. Company CEO Shlomi Raz explains their short and longer-term strategies.
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Updated Date: Fri, 21 Feb 2020 00:00:00 EST.
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GlobeNewswire 02/20/2020 18:57
Company Announced Positive Results from Its Phase 2 Type 1 Diabetes Trial Showing that TTP399 Lowered HbA1C, Decreased the Use of Insulin for Patients and Increased Time in Range. Company Announced Positive Results from Its Phase 2 Type 1 Diabetes Trial Showing that TTP399 Lowered HbA1C, Decreased the Use of Insulin for Patients and Increased Time in Range.
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ClinicalTrials.gov 02/19/2020 12:00
Conditions : Alzheimer Disease; Healthy Volunteer Intervention : Drug: [11C]PBR28 and[18F]NOS Sponsor : University of Pennsylvania Not yet recruiting.
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Business Wire 02/19/2020 07:30
WILMINGTON, Del.--(BUSINESS WIRE)---- $INCY--Incyte Announces Positive Topline Results from Phase 3 TRuE-AD Program evaluating Ruxolitinib Cream in Patients with Atopic Dermatitis.
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FeedNavigator (EU) 02/18/2020 11:23
Background: Several natural products have been reported to elicit beneficial effects against neurodegenerative disorders due to their vitamin E contents. However, the neuroprotective efficacy of palm oil or its tocotrienol-rich fraction (TRF) from the pre-clinical cell and animal studies have not been systematically reviewed. Methods: The protocol for this systematic review was registered in “PROSPERO” (CRD42019150408). This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The Medical Subject Heading (MeSH) descriptors of PubMed with Boolean operators were used to construct keywords, including (“Palm Oil”[Mesh]) AND “Nervous System”[Mesh], (“Palm Oil”[Mesh]) AND “Neurodegenerative D.
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Seeking Alpha 02/17/2020 11:17
TTP399 can prove to be a promising treatment option in T1D indication. There are high chances of azeliragon proving effective in treating dementia in diabetes p.
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News-Medical.net 02/14/2020 06:38
The term astrogliosis may sound unfamiliar to the general public, but this inflammatory process is common to several diseases such as Parkinson's, Alzheimer's, multiple sclerosis and congenital malformations caused by the Zika virus.
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NaturalNews.com 02/13/2020 13:58
Inflammation, which causes the redness and itchiness typical of AD, can be triggered by internal or external elements, such as a bacterial infection.
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