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News-Medical.net 07/19/2019 01:07
The authors note that because stroke doubles the chances of developing dementia, and 90 per cent of strokes are preventable, mitigating stroke risk at the population level provides the most immediate and promising opportunity reduce the rates of both stroke and dementia.
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Benzinga 07/12/2019 10:19
A drug to treat Alzheimer's disease is increasingly proving elusive, despite billions of dollars spent on research and development. Johnson & Johnson (NYSE: )'s Janssen unit; Merck & Co., Inc. (NYSE: ); and Eli Lilly And Co (NYSE: ) in collaboration with AstraZeneca plc (NYSE: ) all scrapped their respective BACE inhibitor programs in 2018. On Thursday, another pharma partnership threw in the towel. Novartis, Amgen Give Up. Novartis AG (NYSE: ), Amgen, Inc. (NASDAQ: ) and the Banner Alzheimer's Institute announced Thursday after the market close their decision to discontinue the clinical trials of CNP520, a BACE1 inhibitor that was being evaluated for preventing in two pivotal Phase 2/3 studies. The decision follows an assessment of unblinde.
In this issue of. JAMA Internal Medicine. , Coupland et al present a very important pharmacoepidemiologic nested case-control study using a database with high external validity and a methodological approach that maximizes internal validity. The study addresses a potentially modifiable risk factor for an important public health issue (the high prevalence of Alzheimer disease and related dementias [ADRD]). The authors report an association between long-term use of strong anticholinergic medications and the diagnosis of ADRD, replicating findings from similar studies from various international populations. Although we believe that articles such as Coupland et al add value to the body of literature describing the association between strong antich.
Scientists have long debated why there seems to be an association between higher levels of education and lower rates of Alzheimer's disease in later life. New research from Johns Hopkins Medicine is suggesting neurodegenerative disease is just as prevalent in more-educated individuals but a greater cognitive reserve can temporarily mitigate the impact of Alzheimer's pathology in one's senior years. .. Continue Reading Higher education doesn’t prevent Alzheimer’s but it can offer a cognitive head start. Category: Medical. Tags:. Alzheimer's Disease. Dementia. Education.

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