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Your search is now limited to «Gene Therapy» expert search. 08/05/2020 04:47 has published the latest research study on Global Gene Therapy in Oncology Market 2020 by Company, Type and Application, Forecast to 2025 that presents a complete overview of the market with a detailed description of the global market.
More from 08/04/2020 21:57
Current TCEs are focused on tumor cell dormancy in breast cancer, precision profiling of blood cancers, clinical trials in pancreatic cancer, immunotherapy in lung cancer, tissue profiling in ovarian cancer, and CAR T therapy for the brain cancer glioblastoma.
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GlobeNewswire 08/04/2020 01:15
About Novartis Commitment to Oncology Cell & Gene Novartis has a mission to reimagine medicine by bringing curative cell & gene therapies to patients worldwide.
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Purpose:. Diffuse intrinsic pontine glioma (DIPG) bears a dismal prognosis. A genetically engineered brainstem glioma model harboring the recurrent DIPG mutation, Activin A receptor type I (ACVR1)-G328V (mACVR1), was developed for testing an immune-stimulatory gene therapy. Experimental Design:. We utilized the Sleeping Beauty transposase system to generate an endogenous mouse model of mACVR1 brainstem glioma. Histology was used to characterize and validate the model. We performed RNA-sequencing analysis on neurospheres harboring mACVR1. mACVR1 neurospheres were implanted into the pons of immune-competent mice to test the therapeutic efficacy and toxicity of immune-stimulatory gene therapy using adenoviruses expressing thymidine kinase (TK) a.
More from Clinical Cancer Research - Recent Issues (abstracts):
Nano-Graphene Oxide-supported APTES-Spermine, as Gene Delivery System, for Transfection of pEGFP-p53 into Breast Cancer Cell Lines.
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Business Wire 07/29/2020 13:49
As part of its Canadian mandate, C3i is excited to expand the Ontario-Quebec corridor and support innovation, ensuring that Canadian technology in cell and gene therapy space can flourish and remain accessible to Canadians,” said Mr. Deschamps.
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PR Newswire 07/24/2020 14:56
The patient's T cells, a type of white blood cell, are collected and genetically modified to include a new gene that facilitates the targeting and killing of the lymphoma cells.
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DNA nanotechnology uses oligonucleotide strands to assemble molecular structures capable of performing useful operations. Here, we assembled a multifunctional prototype DNA nanodevice, DOCTR, that recognizes a single nucleotide mutation in a cancer marker RNA followed by cutting out a signature sequence and using it as an activator for a ‘therapeutic’ function: cleavage of another RNA sequence. The proposed design is a prototype for a gene therapy DNA machine that cleaves a housekeeping gene only in the presence of a cancer‐causing point mutation and suppresses exclusively cancer cells with minimal side effects to normal cells.
This child’s cancer was considered high risk because it had not responded to standard chemotherapy,” explained lead study investigator Meenakshi Hegde, MD, assistant professor of pediatric hematology-oncology at Baylor College of Medicine and Texas Children’s.
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BioPharma Dive 07/14/2020 11:50
The focus is to try to accelerate our scientific understanding broadly in the immuno-oncology space and then specifically with a range of different investigational treatments to gain a much deeper understanding of how these agents are interacting with tumors," said Peter Adamson, Sanofi's new global development head of oncology and pediatric innovation, in an interview ...
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Benzinga 07/10/2020 07:25
Poseida Therapeutics, Inc., a cell and gene therapy company, priced its IPO of 14 million shares at $16 per share, for generating gross proceeds of $224 million.
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