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ClinicalTrials.gov 05/28/2020 07:09
Conditions : Pancreatic Cancer Stage III; Pancreatic Cancer Stage IV; Pancreatic Ductal Adenocarcinoma; Pancreatic Neoplasms Intervention : Procedure: Blood draw Sponsor : Western Connecticut Health Network Recruiting.
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News-Medical.net 05/27/2020 22:07
The biggest takeaway from the surgeons was that pancreatic surgery should be prioritized for patients with non-COVID-19 pancreatic diseases during the pandemic.
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FeedNavigator (EU) 05/27/2020 06:20
Other factors such as alcohol abuse, pancreatitis, nutrition, genetics, family history and chemical carcinogen can contribute to the development of PC 2 DIABETES MELLITUS (DM), A RISK FACTOR OF PANCREATIC CANCER There are three major types of diabetes mellitus (DM): type 1, type 2 and gestational diabetes ...
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In Reply We appreciate Søreide as well as Herb and Stitzenberg’s interest in our study that analyzed travel, optimal location, and centralization of hospitals performing pancreatic resection in California. Both letters highlight the concern that centralization can potentially lead to increased disparities among patients seeking care for surgical care. We agree with the authors that this is an important topic and warrants further discussion and consideration. While previous studies have suggested a possible added travel burden for certain subgroups of patients, to our knowledge, no study has specifically described what factors may be contributing to an increased burden. In fact, our group noted no differences in race/ethnicity or insurance t.
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DoctorsLounge 05/26/2020 13:00
PFS longer in pancreatic ductal adenocarcinoma with versus without homologous recombination deficiency.
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GlobeNewswire 05/26/2020 09:00
We’re proud to share our findings at ASCO 2020, to announce the latest positive Phase 1 results of our lead compound devimistat in the treatment of patients with pancreatic cancer,” said Sanjeev Luther, President and CEO of Rafael Pharmaceuticals.
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Cancer Network 05/24/2020
The primary objective of the study was to determine the biological and clinical significance of HRD determined by several genomic methods in canonical BRCA germline mutations and other putative HR gene mutations in pancreatic cancer.
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Healio News 05/22/2020 09:08
However, we found that this type of treatment can decondition patients and result in substantial muscle loss and weakening in over one-third of pancreatic cancer patients.
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PubMed News (NIH) 05/21/2020
... gene in FNA and cfDNA samples were highly correlated with each other (r=0.98 and 0.97 in samples 1 and 73, respectively) Overall design DNA methylation status was analyzed by MBD-seq in cfDNA from pancreatic cancer patients and corresponding tumor and cfDNA from normal patients.
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Downregulation of miR-486-5p Enhances the Anti-Tumor Effect of 5-Fluorouracil on Pancreatic Cancer Cells [Corrigendum]
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May 20, 2020 - By Jennifer Kennedy. The (PanCAN) recommends for patients. Right now, though, the is causing a lot of challenges and uncertainty around clinical trial enrollment and participation. It’s important for patients and their families to know that, despite these real and significant challenges and concerns, there may still be options to participate in clinical trials at this time. And PanCAN encourages patients to keep pursuing all aspects of the – including seeing a , getting and , and participating in clinical trials – as much as possible at this time. If you are having trouble with any step, for support. Here are some important things to know about clinical trials right now. 1. How trials are operating varies by institution and by.
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Orphan designation: motixafortide, Treatment of pancreatic cancer, 09/01/2020, Positive.
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Business Wire 05/18/2020 08:00
Notably, the data revealed that while prescription medicine expenses have increased as part of the total cost of treating patients with pancreatic cancer over the last ten years, the overall healthcare cost of treating pancreatic cancer patients has gone down.
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Purpose:. Pancreatic cancer remains a disease of high mortality despite advanced diagnostic techniques. Mucins (MUC) play crucial roles in carcinogenesis and tumor invasion in pancreatic cancers. MUC1 and MUC4 expression are related to the aggressive behavior of human neoplasms and a poor patient outcome. In contrast, MUC2 is a tumor suppressor, and we have previously reported that MUC2 is a favorable prognostic factor in pancreatic neoplasia. This study investigates whether the methylation status of three mucin genes from postoperative tissue specimens from patients with pancreatic neoplasms could serve as a predictive biomarker for outcome after surgery. Experimental Design:. We evaluated the methylation status of MUC1, MUC2, and MUC4 promo.
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Cell Reports 05/15/2020 01:21
Obesity is an intrinsic driver of PDAC in mice, leading to a remodeling of beta cells to increase CCK secretion and playing a role early in pancreatic cancer development that can be intercepted by weight loss.
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