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Elevated nuclear auto-antigenic sperm protein promotes melanoma progre.
More from International Journal of COPD:
PubMed News (NIH) 03/20/2019
... current study provides novel profiles of methylation and transcriptomic changes at different stages of carcinogenesis in UVB-irradiation induced NMSC and offer potential targets for prevention and treatment of NMSC at different stages of human skin cancer.
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ClinicalTrials.gov 03/18/2019 10:46
The aim is to identify predictive and prognostic factors for outcome and complications in the surgical treatment of stage IV metastatic melanoma.
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J Oral Maxillofac Surg. 2019 Feb 20. pii: S0278-2391(19)30228-9. doi: 10.1016/j.joms.2019.02.016. [Epub ahead of print]
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Targeted Oncology 03/15/2019 16:09
Pathology indicated that he had grade III squamous cell carcinoma.
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WN.com 03/15/2019 13:11
Over the past few decades, more people have been diagnosed with a form of skin cancer than all other cancers combined and nearly five million people are treated for skin cancer each year in the United States.
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PR Newswire 03/15/2019 07:30
NEW YORK and LA JOLLA, Calif., March 15, 2019 /PRNewswire/ -- Constellation Alpha Capital Corp. (NASDAQ: CNAC) ("Constellation"), a special purpose acquisition company, announced that it has executed a non-binding Letter of Intent to merge with DermTech, Inc. ("DermTech"), a molecular...
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Identifying controlling features of responsiveness to checkpoint blockade therapies is an urgent goal in oncology research. Our group and others have previously shown melanoma tumors resistant to checkpoint blockade display features of mesenchymal transition, including E-cadherin loss. Here, we present the first in vivo evidence that E-cadherin from tumor cells facilitate immune attack, using a B16F10 melanoma mouse model in which E-cadherin is exogenously expressed (B16.Ecad). We find, compared with vector control, B16.Ecad exhibits delayed tumor growth, reduced metastatic potential, and increased overall survival in vivo. Transplantation of B16.Ecad into Rag1−/− and CD103−/− mice abrogated the tumor growth delay. This indicates the anti-m.
More from Cancer Research - Recent Issues (abstracts):
Purpose:. Our study aimed to investigate whether CAF (cancer-associated fibroblasts) were involved in long noncoding RNAs (lncRNA)-regulated radioresponse in esophageal squamous cell carcinoma (ESCC). Experimental Design: By use of lncRNAs PCR array, 38 lncRNAs were screened in esophageal cancer cells and in normal esophageal epithelial cells Het-1A.
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Onclive 03/14/2019 15:27
The FDA has approved 11 drugs or combinations in the past decade for use in patients with melanoma, and the field has changed dramatically since 2013, when SITC issued its first iteration of immunotherapy guidelines for treating patients with melanoma.
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GlobeNewswire 03/14/2019 08:01
The myPath Melanoma test analyzes 23 genes and has proven to be highly accurate in multiple studies at distinguishing melanoma from benign moles (nevi.
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Business Wire 03/14/2019 06:45
Head and Neck Cancer KEYTRUDA is indicated for the treatment of patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) with disease progression on or after platinum-containing chemotherapy.
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Technology Org 03/13/2019 06:30
Seawater bacteria provides leads to fight melanoma.
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Wearable Technologies 03/12/2019 13:29
Melanoma is the deadliest form of skin cancer, affecting more than 130,000 people worldwide each year. Although this cancer is easily visible on the skin, it is hard to differentiate between harmless and harmful moles. Researchers at the University of British Columbia have now developed a simple and compact device that uses laser to can […]
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