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PR Newswire 07/18/2019 08:30
... China represents a little under 20% of the world's population, it accounted for almost 24% of cancer diagnoses and 30% of cancer-related deaths worldwide in 2018, almost a third of which were due to lung cancer and colorectal cancer.
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Protein kinase C-iota-mediated glycolysis promotes non-small-cell lung cancer progression Liu Liu1,*, Bei Lei1,*, Lihua Wang,1 Cheng Chang,1 Hao Yang,2 Jianjun Liu,3 Gang Huang,1–3 Wenhui Xie11Department of Nuclear Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 2Shanghai Key Laboratory for Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, People’s Republic of China; 3Department of Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China*These authors contributed equally to this workPurpose: To determine whether protein kinase C-iota (PKC-iota) is associated with glucose metabolism in non-s.
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ClinicalTrials.gov 07/17/2019 07:53
Condition : Small-cell Lung Cancer Interventions : Drug: ALRN-6924; Drug: Topotecan Sponsor : Aileron Therapeutics Not yet recruiting.
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With over 200,000 people diagnosed with lung cancer every year1 and over 8 million people at high-risk for lung cancer2, early screening is critical to ensure the best chance of survival," said David Webster, NeuroLogica's Chief Operating Officer.
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PubMed News (NIH) 07/17/2019
Contributors : Long T Hoang ; Clara Domingo-Sabugo ; Elizabeth S Starren ; Saffron G Willis-Owen ; Deborah J Morris-Rosendahl ; Andrew G Nicholson ; William M Cookson ; Miriam F Moffatt Series Type : Expression profiling by array Organism : Homo sapiens. Transcriptomic and genetic profiles of tumours and matched normal tissues could help to identify important factors and potential therapeutic targets that contribute to tumorigenesis.
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Reuters.com 07/16/2019 16:03
When hurricanes halt treatment, lung cancer patients die sooner.
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Healio News 07/16/2019 11:29
Leticia Nogueira Patients undergoing radiation for non-small cell lung cancer at the time of a hurricane disaster declaration demonstrated shorter OS than patients who completed treatment under normal conditions, according to a research letter published in JAMA.
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Business Wire 07/16/2019 09:30
NSCLC makes up approximately 85% of lung cancers.
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News-Medical.net 07/16/2019 08:14
By examining both blood samples and tumor tissues from patients with non-small-cell lung cancer (NSCLC), investigators at Massachusetts General Hospital (MGH) have identified markers that can distinguish between major subtypes of lung cancer and can accurately identify lung cancer stage.
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AstraZeneca’s oncology immunotherapy Imfinzi (durvalumab) has been granted orphan drug designation (ODD) for the treatment of small cell lung cancer (SCLC.
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Onclive 07/15/2019 11:28
Alain Borczuk, MD Liquid biopsies are found to be equally as effective as tissue biopsies in the detection of lung cancer, and even more effective than standard tissue biopsies in detecting biomarkers, according to Alain Borczuk, MD.
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GlobeNewswire 07/15/2019 09:42
Our data to date suggests that, in pre-clinical models, PGT is effective in 4 different cell line models of paclitaxel resistance across 3 separate types of cancer, namely ovarian, lung and pancreatic cancers.
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Thorax 07/15/2019 04:35
There are few therapeutic interventions as effective as pulmonary rehabilitation (PR) in the management of the chronic respiratory disease. The scientific evidence base demonstrating the clinical benefit of PR is incontestable, indeed the most recent iteration of the Cochrane systematic review summarising clinical trials of PR in chronic obstructive pulmonary disease (COPD) concluded that no further clinical trials testing effectiveness were needed.1 The gains in physical capacity and health-related quality of life conferred by PR in routine clinical practice are comparable to those seen in clinical trials2 and the available evidence suggests that completion of PR reduces subsequent healthcare costs through a reduction in the number of days.
More from Thorax:
Purpose:. The detection of preexisting EGFR T790M subclones and the assessment of their clinical significance in the pretreatment of patients with EGFR T790M non–small cell lung cancer (NSCLC) remain unclear. Experimental Design:. A total of 179 tumor samples from patients treated or not with a first-generation tyrosine kinase inhibitor (TKI) was analyzed.
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