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PR Newswire 07/18/2019 06:32
Bayer, Bristol-Myers Squibb and Ono Pharmaceutical enter into a clinical collaboration agreement to investigate Stivarga® (regorafenib) and Opdivo® (nivolumab) as combination therapy in patients with metastatic colorectal cancer.
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Bayer 07/18/2019 06:30
Bayer, Bristol-Myers Squibb and Ono Pharmaceutical enter into a clinical collaboration agreement to investigate Stivarga® (regorafenib) and Opdivo® (nivolumab) as combination therapy in patients with colorectal cancer. 07/18/2019 06:00
The OncoBEAM RAS CRC test has an analytical sensitivity down to 0.03% MAF.
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Novel variants of unknown significance in the PMS2 gene identified in patients with hereditary colon cancer.
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Targeted Oncology 07/17/2019 12:12
Regorafenib was approved for the treatment of patients with metastatic CRC whose disease had progressed after prior therapy in 2012.
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Onclive 07/17/2019 11:10
Although therapies aimed at BRAF mutations have shown efficacy in several tumor types, these drugs have demonstrated limited success in studies involving patients with colorectal cancer (CRC.
More from Onclive: 07/16/2019 09:47
... study performed at the Institute for Research in Biomedicine(IRB Barcelona)and published in the journal Nature Communications demonstrates that inhibition of the p38 protein boosts the formation of blood vessels in human and mice colon cancers.
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Population-based screening programs for breast, cervical, and colorectal cancer have been introduced as part of cancer control in many high-income countries.
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ecancer news 07/16/2019 06:03
That is, the participants who followed an inflammatory diet had almost twice the risk of developing colorectal cancer, which is the 4th most frequent cancer worldwide", explains Dr. Mireia Obón.
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Healio News 07/15/2019 15:21
Patients who undergo polypectomy during an initial colonoscopy screening are at higher risk for colorectal cancer, but only if the removed polyps fall into certain categories, according to study results.
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Purpose:. Four consensus molecular subtypes (CMS1–4) of colorectal cancer were identified in primary tumors and found to be associated with distinctive biological features and clinical outcomes. Given that distant metastasis largely accounts for colorectal cancer–related mortality, we examined the molecular and clinical attributes of CMS in metastatic colorectal cancer (mCRC). Experimental Design:. We developed a colorectal cancer–focused NanoString-based CMS classifier that is ideally suited to interrogate archival tissues. We successfully used this panel in the CMS classification of formalin-fixed paraffin-embedded (FFPE) tissues from mCRC cohorts, one of which is composed of paired primary tumors and metastases. Finally, we developed novel.
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Cancer Cell International 07/14/2019 20:00
Compared with traditional biomarkers such as CEA and CA19-9 which have been widely used as tumor markers for CRC in clinical settings, our results also indicated that miR-29 has superior diagnostic properties for CRC screening due to its higher sensitivity, noninvasiveness, and simple detection.
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FeedNavigator (EU) 07/14/2019 08:23
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ETHealthWorld (India) 07/14/2019 03:12
Regorafenib is used to treat colorectal cancer, known to be the sixth most prevalent cancer in India.
More from ETHealthWorld (India): 07/11/2019 22:12
Therefore, the Korean research team investigated the potential mechanisms of branches and leaves of the Chinese sweet plum using SW480 colorectal cancer cells, which are widely used to examine the potency of treatment in cancer prevention and treatment.
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