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Pulmonary Hypertension News 01/21/2019 08:30
In the 24-week Phase 2 MERIT-1 clinical trial (NCT02021292), researchers tested whether 10 mg of Opsumit would be efficacious, safe, and tolerable for patients with inoperable CTEPH.
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GlobeNewswire 01/17/2019 07:00
Zafgen has pioneered the study of MetAP2 inhibitors in both common and rare metabolic disorders and is currently advancing programs for type 2 diabetes, Prader-Willi syndrome and liver diseases.
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ClinicalTrials.gov 01/15/2019 10:59
Data from this trial will also be used to develop a protocol for a subsequent Phase 2 clinical trial in stroke patients.
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Drugs.com 01/14/2019 22:01
Key findings of the HERCULES Phase 3 study of Cablivi include: On the primary endpoint, Cablivi significantly reduced the time to platelet count normalization (p=0.01.
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Business Wire 01/10/2019 07:00
Phase 3 clinical trials continue to evaluate the safety and efficacy of luspatercept in patients with MDS (the MEDALIST trial) and in patients with beta-thalassemia (the BELIEVE trial.
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MedPageToday.com 01/07/2019 10:30
In 2015, a 10-week phase II trial of 220 patients with Alzheimer's disease showed the drug reduced agitation scores by 1 to 2 points over placebo on a 0 (no symptoms) to 12 (daily severe symptoms) scale.
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Healio News 01/07/2019 09:33
A bimatoprost sustained-release implant reduced IOP by approximately 30% over 12 weeks in a second phase 3 study, Allergan announced in a press release.
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PR Newswire 01/07/2019 08:30
Ralinepag (APD811) is being evaluated in a Phase 3 program for pulmonary arterial hypertension (PAH.
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Allergan - CEO Blog 01/07/2019 08:03
Results of this second Phase 3 study with an identical design as the first study, showed that the magnitude of IOP-lowering efficacy with Bimatoprost SR is similar to that observed with topical prostaglandin analogues.
WN.com 01/07/2019 06:21
NEW YORK and MELBOURNE, Australia, Jan. 07, 2019 (GLOBE NEWSWIRE) -- Mesoblast Limited (Nasdaq:MESO; ASX:MSB), world leader in development and commercialization of allogeneic (off-the-shelf) cellular medicines, today announced that it has completed patient recruitment in the events-driven Phase 3 trial of its product candidate Revascor (MPC-150-IM) for advanced chronic heart failure.
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Benzinga 01/07/2019 06:00
Mesoblast Chief Executive Dr Silviu Itescu stated: "Completion of recruitment in this Phase 3 trial, the largest cell therapy trial for heart failure, is a key milestone for Mesoblast and has been achieved on plan.
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FeedNavigator 12/24/2018 09:20
... in increases in ApoA-I and cholesterol efflux similar to those observed in patients with AMI and normal renal function or stage 2 CKD enrolled in the ApoA-I Event Reducing in Ischemic Syndromes I trial.
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PharmaBiz.com 12/22/2018 03:38
Pamrevlumab, an anti-CTGF human monoclonal antibody, is advancing towards Phase 3 clinical development for the treatment of idiopathic pulmonary fibrosis (IPF) and pancreatic cancer, and is currently in a Phase 2 trial for Duchenne muscular dystrophy (DMD.
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FierceMedicalDevices 12/18/2018 07:25
To test whether selatogrel can meet that need, Idorsia initiated two phase 2 trials of the drug.
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The dal-GenE study is evaluating the efficacy of the CETP inhibitor dalcetrapib to reduce clinical cardiovascular events in patients with the AA ADCY9 genotype who have had a recent acute coronary syndrome (ACS.
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