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16,069 results 11/14/2019 13:26
Some of the most biologically active molecules, including synthetic drugs, contain a central, nitrogen-containing chemical structure called an isoquinuclidine. This core has a three-dimensional shape which means it has the potential to interact more favourably with enzymes and proteins than flat, two-dimensional molecules. Unfortunately methods to make isoquinuclidines and the related dehyrdoisoquinuclidines suffer from a number of drawbacks which make it more difficult for scientists to discover new medicinal compounds. A team of researchers led by Prof. Frank Glorius at the University of Münster (Germany) have now published a new method of enabling this reaction. The study was published in the journal Chem. 11/14/2019 13:08
The ocean hosts an inconceivable wealth of marine life and diverse habitats, most of which remains unknown and unseen. International plans to mine minerals from the deep seafloor threaten this largely unexplored biodiversity hotspot. States are currently seeking to develop a legal framework for deep seabed mining. In cooperation with the Heinrich Böll Foundation, an international team of researchers from the Institute for Advanced Sustainability Studies (IASS) has published a new study warning against a rush to exploit deep seafloor resources and calling for coordinated efforts to develop alternative approaches. 11/14/2019 12:08
Chemists from Far Eastern Federal University's School of Natural Sciences (SNS FEFU) have developed a new method to synthesize biologically active derivatives of fascaplysin—the cytotoxic pigment of a sea sponge. For the first time, they obtained a sufficient amount of 3-bromofascaplysin and 3,10-dibromofascaplysin, which were known before but were not available for study. Based on these compounds, scientists synthesized 14-bromoreticulatate and 14-bromoreticulatine—derivatives of reticulatine alkaloids. The resulting article is published in Marine Drugs. 11/14/2019 12:04
Atmospheric nitrogen deposition has a significant impact on both terrestrial and aquatic ecosystems, and alterations in its level will significantly affect the productivity and stability of an ecosystem. In recent years, with the reduction of anthropogenic inorganic nitrogen emissions, interest in organic nitrogen (ON) has increased because it represents a large fraction of total nitrogen. Given this large amount of ON deposition, researchers are interested in identifying its sources. However, scientists find large gaps between ON deposition and emission and therefore suspect that there are missing sources of ON. 11/14/2019 11:13
Axeheads made out of Alpine rock had strong social and economic symbolic meaning in the Neolithic, given their production and use value. Their resistance to friction and breakage, which permitted intense polishing and a re-elaboration of the rock, gave these artefacts an elevated exchange value, key to the formation of long-distance exchange networks among communities of Western Europe. Communities that had already begun to set the value of exchange of a product according to the time and effort invested in producing them. 11/14/2019 10:30
Researchers have laid the basements for a forecast system to foresee the drought impacts a few months ahead. This system will make it possible to take measures in time to manage the consequences of droughts, for instance for shipping, agriculture and nature. A research team from Wageningen University & Research and colleagues from Utrecht and Freiburg published their findings in Nature Communications. 11/14/2019 10:29
Scientists have long theorized that the energy stored in the atomic bonds of nitrogen could one day be a source of clean energy. But coaxing the nitrogen atoms into linking up has been a daunting task. Researchers at Drexel University's C&J Nyheim Plasma Institute have finally proven that it's experimentally possible—with some encouragement from a liquid plasma spark.

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