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PubMed News (NIH) 08/22/2019
Contributors : Bin Shan ; Simon Alsager Series Type : Expression profiling by high throughput sequencing Organism : Homo sapiens. A549 and MDA-MB-231 cells were transfected with the Bloom-specific siRNA. Total RNA was extracted using Trizol at 48 hours after transfection. RNA-SEQ was carried out to profile the gene expression in both culture conditions.
PR Newswire 08/21/2019 17:00
MUNICH and BASKING RIDGE, N.J., Aug. 21, 2019 /PRNewswire/ -- Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) today announced that updated results and new translational research data from two phase 1 studies evaluating investigational antibody drug conjugates (ADCs) U3-1402...
Benzinga 08/21/2019 09:04
AstraZeneca plc (NYSE: ) faced a clinical setback in a study evaluating a combo drug regimen in non-small cell lung cancer, or NSCLC. What Happened. AstraZeneca said a Phase 3 study dubbed NEPTUNE that evaluated its PD-LI inhibitor Imfinzi in combination with tremelimumab, an anti-CTLA4 antibody, versus platinum-based chemotherapy – the current standard-of-care- in previously untreated Stage IV NSCLC did not meet the primary endpoint of improving overall survival. The company noted that ...

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