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LabOnline (Australia) 07/13/2020 10:00
The (TGA) has granted provisional approval to antiviral drug remdesivir as a treatment option for COVID-19, for use in adults and adolescent patients with severe COVID-19 symptoms who have been hospitalised. This makes it the first medication for the novel coronavirus SARS-Cov-2 to be approved in Australia. Remdesivir has been described as the most promising treatment option so far to reduce hospitalisation time for those suffering from severe SARS-Cov-2 infections. By reducing recovery times patients will be able to leave hospital earlier, freeing beds for those in need. However, the product has not been shown to prevent coronavirus infection or relieve milder cases of infection. It will thus only be made available to Australians who are s.
LabOnline (Australia) 07/13/2020 10:00
HEMCO laboratory benches are designed to hold laboratory equipment including fume hoods, tabletop workstations and enclosures. They are available in sizes 1.2, 1.5, 1.8 and 2.4 m wide, with depths of 76 and 91 cm. The 5 cm 2 steel legs are adjustable to heights of 71, 76, 81 and 86 cm. Bench load capacity is tested to 907 kg and options include work surfaces, bottom shelves and seismic levellers. The benches are also available in custom sizes to meet the user’s project specifications.
LabOnline (Australia) 07/13/2020 10:00
Japanese scientists have developed an ultrastable, selective catalyst to dehydrogenate propane — an essential process to produce the key petrochemical substance of propylene — without deactivation, even at temperatures of more than 600°C. Their work has been published in the journal . Propylene is an important raw material for plastics, synthetic rubber, surfactants, dyes and pharmaceuticals.
LabOnline (Australia) 07/12/2020 10:00
Results of the experiments not only reveal new details about the DNA repair process, they also are likely to speed up and aid understanding of the DNA activity that typically causes ageing and many cancers. The team has since filed a provisional patent on their CRISPR technology, which has been described in the journal . CRISPR has in recent years enabled scientists to easily edit DNA sequences and alter gene functions to speed the pace of research on gene-linked conditions. Adapted from a naturally occurring gene editing system found in bacteria, CRISPR uses small sequences of genetic material called RNA as a kind of guide that is coded to match and bind to a specific sequence of genomic DNA within a cell. The CRISPR molecule also contains.
LabOnline (Australia) 07/12/2020 10:00
Blood cancer patients at Melbourne’s and now have access to circulating tumour DNA (ctDNA) genomic testing — an advanced diagnostics test that will potentially save lives and direct patients to alternative treatment options outside of chemotherapy. The development of the test has been made possible by the philanthropic generosity of donors from the and Epworth HealthCare through the , and draws on the scientific knowledge of the Christine and Bruce Wilson Centre for Lymphoma Genomics at the Peter MacCallum Cancer Centre.
LabOnline (Australia) 07/09/2020 10:00
The microscope is said to generate far less noise than customary designs, and its compactness and stability make it suitable for use in operating rooms in hospitals. It has been described in the journal . When investigating how tumours grow, or how pharmaceuticals affect different types of cells, researchers have to understand how molecules within a cell react — and interact. This is possible with modern fluorescence microscopy; however, molecules in cell specimens have to be labelled with fluorescent substances to make them visible, and this can distort the very behaviour of the molecules. Staining with fluorescent markers is also generally unsuitable for in vivo tissues. The newly invented laser microscope does not require fluorescent mar.
LabOnline (Australia) 07/09/2020 10:00
With an intuitive and user-friendly design, SCIEX OS Software is intended to make mass spectrometry more accessible and straightforward for every user. The software is now available on the Echo MS System and the SCIEX Triple Quad 7500 LC-MS/MS System – QTRAP Ready. Data analysis should become easy with shared tools, automation and reduced manual intervention. Auto-detection of sample failures results in auto-corrective action, while review by exception flags means less manual checking of results. Results are meanwhile optimised with powerful integration algorithms. Peak modelling is designed to improve peak finding and integration, requiring less user input and therefore reducing time for data review. Automated result checking and outlier r.
LabOnline (Australia) 07/09/2020 10:00
An international team of researchers has demonstrated in an animal model that two impairments of old age — frailty and immunity decline — can be halted and even partially reversed using a novel cell-based therapeutic approach. Their work has been published in the journal . Elderly people are more prone to infectious diseases as the function of their immune system continuously declines with progression of age, as is apparent during outbreaks of seasonal influenza or other viral diseases such as COVID-19. The efficacy of vaccination in the elderly is similarly reduced, making this age group particularly vulnerable to infectious pathogens and having a high mortality rate. Aged individuals are also commonly affected by frailty that negatively i.
LabOnline (Australia) 07/08/2020 10:00
Alzheimer’s disease (AD) is the most common form of dementia, currently affecting 47 million people worldwide — a figure that is expected to triple to more than 130 million cases by 2050. No effective treatments that cure the disease or slow down its progression have yet been discovered. Now, an early-stage study by researchers has revealed that repurposing an existing asthma drug, salbutamol, offers significant potential as a low-cost and rapid-response option. Their work has been published in the journal . Much Alzheimer’s disease research has focused on the build-up of amyloid plaques in the brain, caused by misfolding of the amyloid-β protein. However, because of disappointing results from numerous therapies targeting amyloid-β aggregat.
LabOnline (Australia) 07/08/2020 10:00
Researchers at have created a non-invasive technology platform for gene delivery into breast cancer cells, utilising low-frequency ultrasound (250 kHz) to detonate microscopic tumour-targeted bubbles like warheads. The technology was developed by ’s Dr Tali Ilovitsh during her postdoctorate research at Stanford, and has been described in the journal . “Microbubbles are microscopic bubbles filled with gas, with a diameter as small as one tenth of a blood vessel,” Dr Ilovitsh explained. “At certain frequencies and pressures, sound waves cause the microbubbles to act like balloons: they expand and contract periodically. This process increases the transfer of substances from the blood vessels into the surrounding tissue. “We discovered that usi.
LabOnline (Australia) 07/08/2020 10:00
Researchers from , in collaboration with and the (JASRI), have reduced the beam diameter of an X-ray free-electron laser to 6 nm in width. Their breakthrough, described in the , brings the utility of these lasers for imaging structures closer to the atomic level than was previously possible. To ‘see’ extremely small and otherwise invisible objects, and observe ultrafast chemical processes, researchers commonly use synchrotron X-ray facilities. X-ray free-electron lasers are an alternative that can — in principle — image atomic-scale detail of, for example, a virus particle on the timescale of an electron transition, without damaging the particle. To do this, you need an incredibly bright X-ray laser that focuses extremely fast laser pulses
LabOnline (Australia) 07/06/2020 10:00
The world’s deep oceans are warming at a slower rate than the surface, but it’s still not good news for deep-sea creatures. That’s according to an international study published in the journal and led by (UQ) PhD student Isaac Brito-Morales, who set out to look at how ocean life was responding to climate change. “We used a metric known as climate velocity which defines the likely speed and direction a species shifts as the ocean warms,” Brito-Morales said. “We calculated the climate velocity throughout the ocean for the past 50 years and then for the rest of this century using data from 11 climate models. “This allowed us to compare climate velocity in four ocean depth zones — assessing in which zones biodiversity could shift their distribut.
LabOnline (Australia) 07/06/2020 10:00
Researchers from the (UPV/EHU) have found that natural by-products from the food industry, normally discarded in industrial processes, are an excellent source of biomaterials for producing biomedical devices. The team from UPV/EHU’s and groups developed a novel device comprising soy protein and chitin, which formed a matrix with a porous, interconnected microarchitecture similar to that of certain body tissues.
LabOnline (Australia) 07/06/2020 10:00
Don Whitley Scientific has launched its smallest anaerobic workstation: the Whitley A20 Workstation. The anaerobic chamber provides good conditions for the processing, incubation and examination of samples without exposure to atmospheric oxygen, and is gas efficient. It can accommodate 240 x 90 mm Petri dishes while retaining a generous working area, and will hold up to 400 plates for emergency anaerobic incubation. The product serves as a first step up from using anaerobic jars to using a workstation. It has the same precise control of parameters as Don Whitley’s larger workstations, ensuring appropriate anaerobic conditions are maintained. Users can check their plates as often as they like and perform tasks inside the workstation without
LabOnline (Australia) 07/05/2020 10:00
Neuroscientists have shed a new light on the mechanisms responsible for familial migraine, showing that a genetic dysfunction in specific brain cells of the cingulate cortex area strongly influences head pain occurrence. Their research has been published in the journal . Migraine is one of the most disabling disorders, affecting one in seven people and causing a tremendous social and economic burden. Several findings suggest that migraine is a disease affecting a large part of the central nervous system and characterised by a global dysfunction in sensory information processing and integration, which also occurs between migraine episodes (interictal period). For example, patients with migraine exhibit increased cortical responses to sensory.
LabOnline (Australia) 07/05/2020 10:00
Azure Biosystems imagers cover the full spectrum of capabilities for documentation and quantitative analysis of gels, Western blots, slides, tissue samples, small animal models, plants and more. Users can choose from one of the Azure imagers for general lab imaging needs or the Sapphire Biomolecular Imager for high flexibility and performance on blots, gels, plates, microarrays, phosphor imaging, tissue and small animal models. Azure imagers offer fast, sensitive, high-resolution, 9 MP, CCD-based detection in a small, benchtop-friendly footprint. They are multichannel, multimodal imagers, with near-infrared, visible light and UV excitation channels. They can be used to detect Cy dyes, Alexa dyes, Safe dyes, Trihalo compound based gels and m.
LabOnline (Australia) 07/05/2020 10:00
Ultraviolet germicidal irradiation has long been an accepted disinfection method in medical fields. The light breaks down, or inactivates, viruses and bacteria at a core level. Earlier this year, a study found UV-C effective at disinfecting both steel surfaces and fabrics of SARS-CoV-2. Now global lighting company , together with the (NEIDL) at , has validated the effectiveness of its own UV-C light sources on the inactivation of the virus. Dr Anthony Griffiths and his team at treated inoculated SARS CoV-2 material with different doses of UV-C radiation coming from a Signify light source and assessed the inactivation capacity under various conditions. The team applied a dose of 5 mJ/cm 2 , resulting in a 99% reduction of the SARS-CoV-2 viru.
LabOnline (Australia) 07/02/2020 10:00
Known as the Droplet and Aerosol Reducing Tent (DART), the device was designed in collaboration with doctors from the (NUH). The multidisciplinary team took less than two months to develop DART and validate its performance. Extra protection for frontline healthcare workers. The COVID-19 pandemic has dramatically increased the need for infection control when intubating patients. Intubation is the placement of a flexible plastic tube into the windpipe to maintain an open airway or to serve as a conduit through which to administer certain drugs. The removal of this plastic tube is known as extubation. These are risky procedures that may put healthcare workers in danger of becoming infected. Evidence from the SARS outbreak in 2003 showed that he.

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