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Medical Xpress - Cancer News 12/07/2019 10:09
The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) today announced results from an extended follow-up analysis of patients in its randomized Phase 3 clinical trial, E1912. The results show that the combination of ibrutinib, a Bruton's tyrosine kinase inhibitor, and the antibody therapy rituximab, continue to provide superior progression-free survival and overall survival compared to standard chemoimmunotherapy for patients (aged 70 or younger) with previously untreated chronic lymphocytic leukemia (CLL). The analysis provides new safety and efficacy information on the patients in E1912 who completed ibrutinib plus rituximab therapy and continued to receive ibrutinib for as long as it remained effective.
Medical Xpress - Cancer News 12/07/2019 10:08
For older patients with acute myeloid leukemia (AML), the prospects for success of a stem cell transplant can often be predicted based on the particular set of genetic mutations within the tumor cells, investigators at Dana-Farber Cancer Institute and other research centers will report today at the 61st American Society of Hematology (ASH) Annual Meeting.
Medical Xpress - Cancer News 12/07/2019 10:07
A new, experimental immunotherapy can put patients with B-cell non-Hodgkin lymphoma (NHL) that is resistant to or has come back after multiple other therapies, including CAR T therapy, into remission. A global, multi-center trial found almost half of patients with slow growing lymphomas had complete responses to the antibody called mosunetuzumab. Among patients on the study whose lymphoma progressed after CAR T therapy, 22 percent went into complete remission when treated with the drug. Stephen J. Schuster, MD, director of the Lymphoma Program at the Abramson Cancer Center of the University of Pennsylvania, will present the findings in a plenary session as well as during the press program at the 61st American Society of Hematology Annual Me.
Medical Xpress - Cancer News 12/05/2019 03:01
Prostate cancer is the most common cancer in men in the UK , yet we still don't know all of its causes. The largest ever study to use genetics as a measurement for physical activity to look at its effect on prostate cancer, reveals that being more active reduces the risk of prostate cancer. Over 140,000 men were included in the study, of which, 80,000 had prostate cancer.
Medical Xpress - Cancer News 12/03/2019 09:20
Cancer patients own reporting of their quality of life can be important in predicting the outcome of their disease, say researchers from the European Organisation for Research and Treatment of Cancer (EORTC). Until recently, reports from clinicians on issues such as patient age and tumor status were used primarily in determining prognoses, but now researchers have shown conclusively that patient-reported outcomes (PROs) have considerable value in predicting survival.
Medical Xpress - Cancer News 11/29/2019 07:49
What molecular event happens for prostate cancer to progress faster and to be deadlier when patients eat a high-fat diet? This is the question Dr. David P. Labbé, a scientist at the Research Institute of the McGill University Health Centre (RI-MUHC), and his colleagues recently elucidated. In a study published in Nature Communications, they showed that saturated fat intake induces a cellular reprogramming that is associated with prostate cancer progression and lethality. These findings could have a clinical utility in identifying patients at higher risk of a more aggressive, lethal disease. In addition, they suggest that dietary intervention involving the reduction of animal fat, and specifically saturated fat consumption in men with early-


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