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Your search is now limited to «Leukemia» expert search. 07/23/2019 08:07
Conditions : CD19 Positive; CD22 Positive; Minimal Residual Disease; Progressive Disease; Recurrent B Acute Lymphoblastic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Non-Hodgkin Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Non-Hodgkin Lymphoma Interventions : Biological: Autologous CD19/CD22 Chimeric Antigen Receptor T-cells; Drug: Cyclophosphamide; Drug: Fludarabine Sponsors : M.D. Anderson Cancer Center; National Cancer Institute (NCI) Not yet recruiting. 07/23/2019 08:06
Conditions : Non-Hodgkin's Lymphoma, Relapsed; Chronic Lymphoid Leukemia in Relapse; Non-Hodgkin's Lymphoma Refractory; Chronic Lymphocytic Leukemia; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic; B-cell Chronic Lymphocytic Leukemia; B-cell Non Hodgkin Lymphoma Interventions : Genetic: PBCAR20A; Drug: Fludarabine; Drug: Cyclophosphamide Sponsor : Precision BioSciences, Inc. Not yet recruiting. 07/23/2019 07:03
Following MTD/MAD identification, three separate safety run-in cohorts in neuroblastoma, acute myeloid leukemia (AML), and acute lymphoblastic leukemia (ALL) will be conducted to identify the recommended Phase 2 dose (RP2D) of idasanutlin in each combination, with chemotherapy or venetoclax.
Healio News 07/21/2019 08:00
CHICAGO — Bijal D. Shah, MD, associate professor in the department of malignant hematology at Moffitt Cancer Center, spoke with HemOnc Today at ASCO Annual Meeting about the ZUMA-3 study. The phase 1/phase 2 study evaluated KTE-X19 (Kite Pharma), an investigational anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for adults with relapsed/refractory acute lymphoblastic leukemia. Shah provided an overview of end-of-phase-1 results. “We were able to identify a cell dose and a toxicity management algorithm that seems to come with highly encouraging response rates and highly. 07/19/2019 06:50
Activating mutations in the fms like tyrosine kinase 3 (FLT3) gene are observed in approximately 30% of patients with newly diagnosed acute myeloid leukemia (AML.
PubMed News (NIH) 07/19/2019
Status Public on Jul 19, 2019 Title Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection Organism Homo sapiens Experiment type Expression profiling by high throughput sequencing Summary Chemotherapy-resistant cancer recurrence is a major cause of mortality.


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