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Healio News 09/18/2019 18:45
LAS VEGAS – Jason Miller, OD, MBA, said he uses technology to better treat ocular surface disease in his practice and create an experience for the patient. Miller spoke here at the Global Contact Lens Forum, held during Vision Expo West. A multitude of traditional diagnostic tools are available, including staining and questionnaires, he said. Miller uses the TearScience Meibomian Gland Evaluator. He explained that a predetermined pressure is applied on the lid and held 10 to 15 seconds. “Do it nasally, centrally and temporally – on both the upper and lower lids – and.
Healio News 09/18/2019 17:20
Results from a systematic review and meta-analysis revealed 13 risk factors for intrahepatic and extrahepatic cholangiocarcinoma, the most significant of which included biliary cysts and stones, cirrhosis, hepatitis B and hepatitis C. Additionally, although diabetes was not among the strongest risk factors, increasing global rates of diabetes may be contributing to rising rates of cholangiocarcinoma (CCA).
Healio News 09/18/2019 17:07
LAS VEGAS – The use of aberrometry can provide peace of mind when patients do not see 20/20, according to a speaker here at Vision Expo West. “The biggest thing an aberrometer helps us with is an objective measure of vision quality,” Chris A. Smiley, OD, said at the Global Contact Lens Forum “In optometry school we were taught if a patient doesn’t see 20/20, we have to refer it to figure out why,” he said. “We can use aberrometry to help us figure this out.” He shared a case of a 65-year-old patient with diabetes and a cataract that he initially.
Healio News 09/18/2019 17:04
The FDA has granted Gazyva breakthrough therapy designation for the treatment of adult patients with lupus nephritis, according to a Genentech press release. Originally approved by the FDA in 2013 for the treatment of adults with previously untreated chronic lymphocytic leukemia, Gazyva (obinutuzumab, Genentech) was subsequently approved in 2017 for the treatment of adults with previously untreated advanced follicular lymphoma. For the purpose of treating complications linked to systemic lupus erythematosus, the breakthrough designation pairs Gazyva with standard of care practices, such as.
Healio News 09/18/2019 17:00
PARIS — In a series of 125 patients looking at the precision of capsulotomies created with the CAPSULaser compared with manual technique before routine cataract surgery, Erik L. Mertens, MD, FEBOphth, of Medipolis Eye Centre in Antwerp, Belgium, found the selective laser capsulotomy technique to be better in sizing accuracy, circularity and centration.
Healio News 09/18/2019 16:24
Combination tofacitinib and oral minoxidil therapy in alopecia areata may be superior to tofacitinib alone, according to findings published in the Journal of the American Academy of Dermatology. “Janus kinase inhibitors are emerging as an important therapy for severe alopecia areata and the possibility of increasing efficacy without increasing Janus kinase inhibitor dosage (and immunomodulation and cost of treatment) would be welcome,” Carlos G. Wambier, MD, PhD, of the department of dermatology at Yale University School of Medicine, and colleagues wrote. Researchers reviewed cases.
Healio News 09/18/2019 15:50
LAS VEGAS – Justin Schweitzer, OD, said here at Vision Expo West that the increase in the number of glaucoma patients necessitates optometrists’ involvement in both long- and short-term postoperative management. ODs must monitor patients who underwent minimally invasive glaucoma surgery for hyphema, hypotony and IOP spikes. In addition, glaucoma medications should be removed one at a time, after 1 week, once target pressure is met. Disclosure: Schweitzer reports no relevant financial disclosures.
Healio News 09/18/2019 14:22
Patients with inflammatory bowel disease who responded to certain therapies exhibited consistent changes in their gut microbiome, which could lead to new opportunities for precision medicine, according to results of a meta-analysis. “Even though the microbiome appears to play a key role in IBD pathogenesis and advances in technology increasingly allow rapid microbiome sequencing, the use of the microbiome as a predictive biomarker of treatment response has been poorly explored,” Fernando Magro, MD, PhD, of the department of biomedicine at the University of Porto in Portugal, and.
Healio News 09/18/2019 14:00
Increased long-term antibody response to cytomegalovirus and decreased response to Toxoplasma gondii were linked to bipolar disorder, according to findings published in JAMA Psychiatry. “Exposure to infectious agents and the associated immune activation underscore conceptualizing bipolar disorder as a multisystem inflammatory disease of the brain and the body,” Mark A. Frye, MD, from the department of psychiatry & psychology at Mayo Clinic, and colleagues wrote. “The disease risk or biologic mechanism of infectious environmental exposure, early immune activation, acute.
Healio News 09/18/2019 14:00
OCU400, a gene therapy candidate, has received a second orphan drug designation from the FDA for the treatment of CEP290 mutation associated retinal disease, Ocugen announced in a press release. The CEP290 mutation is associated with Leber congenital amaurosis, Bardet-Biedl syndrome, Joubert syndrome, Senior-Loken syndrome and Meckel-Grüber syndrome. “Orphan designation for this indication supports the goal of our modifier gene therapy platform to treat a variety of inherited retinal diseases with a single gene therapy,” Shankar Musunuri, PhD, MBA, Ocugen chairman, CEO and.
Healio News 09/18/2019 13:50
None of the more than 1,400 patients with prediabetes were formally referred to the CDC’s National Diabetes Prevention Program, according to findings recently published in the Journal of the American Board of Family Medicine. “The fact that there is a highly effective (better than the effectiveness of most medicines!) lifestyle intervention — the National Diabetes Prevention Program — to prevent progression to type 2 diabetes is wonderful,” James W. Keck, MD, MPH, a physician within the department of family and community medicine at the University of Kentucky,
Healio News 09/18/2019 13:48
In a letter released earlier this month, the Medicare Payment Advisory Commission urged CMS Administrator Seema Verma to not implement its ESRD Treatment Choices model, a program that would provide financial incentives of up to 3% to nephrologists and dialysis providers who increase the number of patients treated with home dialysis or who achieve a higher rate of kidney transplantation.

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