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Researchers at Karolinska Institutet in Sweden have carried out the first randomised trial of civilians with acute conflict-related wounds at two hospitals in areas affected by armed conflict. The study, which is published in The Lancet Global Health, shows that a new, more costly method of wound treatment is not more effective than standard treatment. The researchers hope to inspire new research projects in conflict zones that could improve the care for these vulnerable patients.
A multidisciplinary study led by UB researchers has developed a new experimental tool that enables the application of focalized damage on an in vitro neuronal network of only a few millimetres and record the evolution of the whole network. The objective is to understand the response mechanisms that take place in the brain neuronal circuits, and which prevent a total propagation of the damage while they recover the functionality of the affected circuits. One of the main conclusions is that the network quickly activates self-regulation mechanisms that reinforce the existing connections and restore the functionality of the circuit.
The recent coronavirus (COVID-19) outbreak presents enormous challenges for global health. To aid the global effort, Broad Institute of MIT and Harvard, the McGovern Institute for Brain Research at MIT, and our partner institutions have committed to freely providing information that may be helpful, including by sharing information that may be able to support the development of potential diagnostics.
Acute myeloid leukemia (AML), a blood cancer affecting both adults and children, requires more than one genetic "hit" to develop. As we age, many of us acquire a mutation that enables certain of our blood cells to multiply faster than others, forming their own distinct population. This first hit, known as "clonal hematopoiesis of indeterminate potential," or CHIP, isn't necessarily harmful.
While the mortality rate for cervical cancer has declined dramatically since the 1970s, more than 400 Canadian women succumbed to the disease in 2019. A new paper, published in the International Journal of Cancer, by researchers at McGill University's Faculty of Medicine, supports a novel alternative to standard pap smears and human papillomavirus (HPV) tests, one that has the potential to detect cervical cancer earlier than ever before.
Although most neurotransmitters perform the same basic role, they are not fungible. Each takes the baton from an incoming action potential and passes the neural message across the synaptic divide, yet each flavor of transmitter adds its own unique twist. Simply put, they have completely different metabolic actions. Properly functioning brains require the eclectic services of all of them, everywhere, all the time. In nearly every remote outpocket of the brain, whether retina, olfactory bulb, or even transmitter-specific projection nuclei of the brainstem, all of the major transmitter systems can be found within each.

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