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Healio News 08/15/2020 10:00
Most optometrists report proactive use of cycloplegia but may still wish to have more evidence-based resources on which to base their decisions, according to a study in Ophthalmic and Physiological Optics. “Despite considerable clinical benets, the use of cycloplegic eye drops incur a number of undesirable side effects for children,” Lesley A. Doyle, PhD, Biomedical Sciences Research Institute, University of Ulster, and colleagues wrote. “Whilst practitioners may be aware of the benets of cycloplegia when assessing refractive error, there is limited clinical guidance.
Healio News 08/15/2020 09:00
Etrolizumab, an investigational drug developed by Genentech, failed to meet the primary maintenance endpoints in several phase 3 trials and had mixed results in other induction studies, according to a company press release. Researchers evaluated the drug, a dual anti-integrin that inhibits alpha4beta7 and alphaEbeta7, in a trial program comprising eight randomized-controlled trials, as well as two open-label extension and safety monitoring studies. In the studies that explored the drug’s efficacy in inducing remission in patients with moderate to severe ulcerative colitis, etrolizumab met.
Healio News 08/15/2020 08:54
The disproportionate rate of diabetes in Black communities coupled with the COVID-19 pandemic laid bare structural inequities that diabetes care and education specialists have an opportunity to change, according to a speaker. “We are in the midst of an unprecedented time — a horrible pandemic that has exposed racial health inequities, and then the killing of Black Americans that have been very public,” Uché Blackstock, MD, founder and CEO of Advancing Health Equity and former associate professor of emergency medicine at the New York University School of Medicine, told.
Healio News 08/15/2020 08:30
Different anti-VEGF regimens may not result in superior vision benefits compared with ranibizumab for neovascular age-related macular degeneration, according to a meta-analysis presented at the virtual American Society of Retina Specialists meeting. “Although some studies have compared the efficacies of different anti-VEGF therapies for wet AMD, no single trial can draw comparison between every anti-VEGF agent and dosing regimen available,” Diana V. Do, MD, of Byers Eye Institute at Stanford University, said in her presentation. Using a network meta-analysis approach, Do and.
Healio News 08/15/2020 08:00
Among patients with STEMI, 1 in 4 had troponin concentrations less than the European Society of Cardiology-recommended rule-in threshold for accelerated diagnostic testing at presentation, researchers reported. Although patients who presented within 2 hours of symptom onset were more likely to have concentrations less than the 99th percentile, just 1 in 6 had troponin concentrations less than the diagnostic threshold (5 ng/L). “During myocardial infarction, abrupt coronary occlusion may prevent the release of troponin into the circulation until reperfusion has occurred,” Ryan.
Healio News 08/15/2020 07:00
NuVasive Inc. reported decreased net sales and operating margin in its second-quarter 2020 financial results, according to a press release. Despite an “upward monthly volume trend” in June, NuVasive experienced a decrease in total net sales from $292.1 million to $203.6 million, a 30.3% decrease compared to its second-quarter 2019. The company also saw a generally accepted accounting principles (GAAP) operating margin decrease of 18.3% compared to last year and a GAAP diluted net loss per share of -$0.98, according to the release. “NuVasive’s second-quarter performance.
Healio News 08/15/2020 07:00
Jae Jung, PhD, has been appointed chair of Cleveland Clinic Lerner Research Institute’s department of cancer biology. Jung will oversee the department’s work to improve understanding of the biological underpinnings of cancer, including disease manifestation and genetic or molecular pathways. He also will serve as director of the new Center for Global and Emerging Pathogens Research. Center staff will focus on various public health threats such as SARS-CoV-2 — which causes COVID-19 — and Zika virus. “Jae Jung is a brilliant and global leader in research into the deep.
Healio News 08/14/2020 16:24
Maternal exposure to heat, ozone or fine particulate matter related to climate change was associated with adverse pregnancy outcomes such as preterm birth and low birth weight, according to a systematic review published in JAMA Network Open. The link, based on findings from 57 studies containing data on nearly 32.8 million births, was observed in all regions of the United States. The effects of extreme heat and air pollution were especially pronounced among women with asthma and those who are Black, study co-author Nathaniel DeNicola, MD, an assistant professor of obstetrics and gynecology at.
Healio News 08/14/2020 16:17
Children whose mothers used cannabis during pregnancy are at a higher risk for autism compared with children whose mothers did not, according to a study published in Nature Medicine. “Despite these warnings, there is evidence that more people are using cannabis during pregnancy,” Mark Walker, MD, chief of the department of obstetrics, gynecology and newborn care at The Ottawa Hospital and professor at the University of Ottawa, said in a press release. “This is concerning, because we know so little about how cannabis affects pregnant women and their babies. Parents-to-be.
Healio News 08/14/2020 16:00
Better preoperative, intraoperative and postoperative technologies, plus fears from the pandemic, may lead to increased interest in the premium lens market, according to a speaker at Octane’s virtual Ophthalmology Technology Summit. Premium lens procedures increased nationally from April to June. Patients have cited the availability of government subsidies, fears from the pandemic and better education as reasons to invest in upgraded lenses, Inder Paul Singh, MD, said at the meeting. “People have fears of touching their eyes right now, either with glasses or contact lenses. It’s.
Healio News 08/14/2020 14:45
The AAP updated its guidance regarding COVID-19-related advice for cloth face coverings, testing protocols and personal protective equipment in the care of children during the pandemic. The guidance draws from the latest available evidence, the AAP said. Cloth face coverings The AAP advised that all children aged 2 years or older can wear cloth face coverings safely, “including the vast majority of children with underlying health conditions.” “Children are incredibly adaptable and resilient,” AAP President Sally Goza, MD, FAAP, said in a press release about the guidance. “Just.
Healio News 08/14/2020 14:04
Results from a pilot trial showed taking at-home blood pressure measurements was feasible for patients receiving in-center hemodialysis, with high demonstrated adherence rates. “Observational studies have reported that while the association of pre-dialysis [systolic blood pressure] SBP and adverse clinical outcomes is U-shaped, the association between out-of-dialysis-unit SBP and risk of mortality and CVD is linear in the same patients,” Nisha Bansal, MD, MAS, of the Kidney Research Institute at the University of Washington, and colleagues wrote. “Many opinion leaders and.
Healio News 08/14/2020 13:57
An FDA advisory committee voted 8-2 in favor of approval of the cell therapy remestemcel-L for the treatment of children with steroid-refractory acute graft-versus-host disease. The FDA’s Oncologic Drugs Advisory Committee (ODAC) supported approval despite concerns about limited efficacy data for remestemcel-L (Ryoncil, Mesoblast Ltd.). Results of randomized trials showed the therapy failed to confer significant benefit; however, those results were conducted in adults rather than children. Results of a single pediatric arm of one phase 3 clinical trial showed an acceptable overall response.
Healio News 08/14/2020 13:49
Despite the pandemic, 2020 has been a busy year for the Association of Women in Rheumatology, according to Grace C. Wright, MD, PhD, the organization’s president. “We have been really fortunate to be able to go to certain places live,” she said in welcoming attendees to the organization’s virtual National Conference. “We have been able to add chapters around the world.” International chapters of AWIR have taken foothold in Bangladesh, Brazil, Canada and Pakistan, according to Wright. These locations complement established AWIR chapters in India, Italy and.
Healio News 08/14/2020 13:13
The Association of Diabetes Care & Education Specialists began 2020 with a new name and new vision but was soon confronted with unprecedented public health emergencies that offered both challenges and opportunities, according to a speaker. “The year that began as the dawning of the diabetes care and education specialist turned almost overnight into the year of SARS-CoV-2, and then social unrest,” Kellie Antinori-Lent, MSN, RN, ACNS-BC, BC-ADM, CDCES, FADCES, a diabetes clinical nurse specialist at the University of Pittsburgh Medical Center Shadyside Hospital and 2020 ADCES.
Healio News 08/14/2020 13:00
The CDC’s annual Contact Lens Health Week will work with the American Optometric Association and Health Care Alliance for Patient Safety to raise awareness of healthy lens practices Aug. 17 to 21. The week will highlight various topics such as the risk associated with improper use, the importance of regular visits to an eye care provider and preventing transmission of COVID-19. “Although there’s no evidence to date that suggests contact lens wearers are more at risk for contracting COVID-19 than eyeglass wearers, ensuring the safety of our contact lens wearing patients remains.
Healio News 08/14/2020 12:55
Osteochondral autograft transplantation has shown positive clinical outcomes in the treatment of medium-sized osteochondral lesions of the talus, according to a study by researchers at Hospital for Special Surgery. Between 2015 and 2018, Taylor Cabe, BS, and colleagues from HSS analyzed 50 patients with osteochondral lesions of the talus (OLTs). Overall, 27 patients were treated with microfracture with extracellular matrix augmentation (MFX) and 23 patients were treated with osteochondral autograft transplantation (OAT). Researchers collected patients’ foot and ankle outcome score (FAOS)
Healio News 08/14/2020 12:49
Endovascular therapy for stroke due to anterior circulation large-vessel occlusion resulted in modestly better functional outcomes compared with medical therapy, even with presentation delay of more than 16 hours, researchers reported. The study, published in JAMA Neurology, assessed the baseline characteristics of 150 patients with acute ischemic stroke, internal carotid artery or middle cerebral artery occlusion, baseline NIH Stroke Scale score of at least six and were admitted at least 16 hours from the time the patients were last known well. “Patients with acute ischemic stroke and.
Healio News 08/14/2020 12:40
The FDA approval of brexucabtagene autoleucel represents a major step forward for the treatment of adults with relapsed or refractory mantle cell lymphoma, experts told Healio. “The approval ... is practice changing,” Henry Chi Hang Fung, MD, FACP, FRCPE, chair of the department of bone marrow transplant and cellular therapies at Fox Chase Cancer Center, told Healio. “It’s a big deal that we now have a new treatment option for patients with an unmet need — that is, refractory disease.” The FDA granted accelerated approval to brexucabtagene autoleucel.
Healio News 08/14/2020 12:40
Researchers found current Meriri-based Incentive Payment System and future public reporting of physician scores for outcome measures used flawed methodology, questioning its ability to differentiate between high- and low-performing ophthalmologists. In this study, John T. Thompson, MD, assistant professor at The Wilmer Institute of The Johns Hopkins University and associate clinical professor at The University of Maryland, and colleagues examined the reliability of all 29 current Medicare Merit-based Incentive Payment System (MIPS) clinical quality outcome measures for ophthalmology by.

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