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Pulmonary Hypertension News 10/18/2019 08:30
Adcirca (tadalafil) helped to improve survival in dogs with pulmonary hypertension (PH), a new study suggests. Knowing the underlying conditions associated with PH can lead to improved health outcomes in dogs, the study stated. The findings might also prove to be important in understanding the disease in humans. The study, titled “Pulmonary hypertension secondary to […]. .
Pulmonary Hypertension News 10/17/2019 08:00
Treatment with Adcirca (tadalafil) plus Opsumit (macitentan) can provide functional benefits and lessen symptoms in newly diagnosed patients with pulmonary arterial hypertension (PAH), results from a clinical trial show. The data will be discussed at the upcoming CHEST Annual Meeting 2019, to be held Oct. 19-23 in New Orleans, La. An oral presentation, titled “Initial […]. .
Pulmonary Hypertension News 10/16/2019 08:00
To help those with heart and circulatory disorders live longer and better lives, the British Heart Foundation (BHF) has awarded the University College London (UCL) a £1 million grant (about $1.28 million) over five years. Specifically, funding from the BHF Research Accelerator Award will help UCL build a research team that will focus on data science […]. .
Pulmonary Hypertension News 10/15/2019 13:04
The mechanics of pulmonary hypertension (PH) create a cascade of events that affect the cardiovascular system, kidneys, respiratory system, and digestive system. Though symptoms, which persist over time, primarily lead to changes in breathing and aerobic endurance, the lack of blood flow, extra exertion, hormone fluctuations, and inflammation caused by the disease have an effect […]. .
Pulmonary Hypertension News 10/14/2019 10:00
In last week’s column, I shared how the Make-A-Wish Foundation granted my son Cullen’s prodigious wish to meet President George W. Bush in 2008. To be on the receiving end of this amazing nonprofit organization is extraordinary. The foundation creates adventures that far exceed expectations. To be on the giving end is equally joyous. In August […]. .
Pulmonary Hypertension News 10/14/2019 08:30
Respira Therapeutics has regained full worldwide research, development, and licensing rights over its inhaled medicine-device combination product, called RT234, for the treatment of pulmonary arterial hypertension (PAH). This follows the decision of its partner United Therapeutics to terminate the collaboration with Respira, which was established in April 2017. RT234 is an inhaled therapy being developed […]. .
Pulmonary Hypertension News 10/11/2019 08:00
Pulmonary hypertension contributes to markedly poorer outcomes and doubles a risk of death in people with moderate-to-severe problems in the heart’s tricuspid valve, a condition known as tricuspid regurgitation, a study from Europe reports. The study, “Impact of pulmonary hypertension on outcome in patients with moderate or severe tricuspid regurgitation,” was published in the journal […]. .
Pulmonary Hypertension News 10/10/2019 08:00
Measuring the levels of an inflammatory protein known as HMGB1 may help diagnose persistent pulmonary hypertension of the newborn (PPHN) and monitor its progression, according to a study in patients and in a rat model. The research, “High mobility group box 1 protein (HMGB1) as biomarker in hypoxia-induced persistent pulmonary hypertension of the newborn: a […]. .
Pulmonary Hypertension News 10/09/2019 08:30
Loss of a hormone called secretin (SCT) induces hypertension, scarring, and structural alterations in the heart and lungs, a study in mice reports. The study “Loss of secretin results in systemic and pulmonary hypertension with cardiopulmonary pathologies in mice” was published in the journal Nature Scientific Reports, and led by a team from Hong Kong. SCT […]. .
Pulmonary Hypertension News 10/07/2019 16:00
In last week’s column, I wrote about the challenges of making time for rest. This week, I want to address another significant lifestyle adjustment I’ve made since my diagnosis: my diet. A low-salt diet is recommended for those with pulmonary hypertension. Unfortunately, all of my favorite foods are incredibly salty, including cheese, chips, and pizza. […]. .
Pulmonary Hypertension News 10/07/2019 10:00
In 2008, my 8-year-old son was diagnosed with pulmonary hypertension (PH). Being told that Cullen had an incurable, life-threatening illness was traumatic. It was impossible to imagine that there would be happy days following that news. That year, two wish granters from the Make-A-Wish Foundation visited Cullen at home. Debbie Hanan and Michelle McLendon wanted to […]. .
Pulmonary Hypertension News 10/07/2019 08:00
Oral treatment with rodatristat ethyl is safe and well-tolerated, according to results from two completed Phase 1 clinical studies in healthy volunteers. These positive results support advancing the investigational therapy into Phase 2 studies involving people with pulmonary arterial hypertension (PAH), the treatment’s developer says. The most recent findings on Altavant Sciences’ lead candidate were […]. .
Pulmonary Hypertension News 10/04/2019 08:00
Halting a protein called Slug may help reduce the severity of increased blood pressure related to lung scarring — a condition called pulmonary hypertension (PH) secondary to pulmonary fibrosis, or PF-PH, a new animal study shows. The study, “Histological hallmarks and role of Slug/PIP axis in pulmonary hypertension secondary to pulmonary fibrosis,” was published in […]. .

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