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FeedNavigator (EU) 02/25/2020 00:11
Similarly, cytokines and chemokines such as those secreted from obese visceral WAT can induce expression of endothelial adhesion molecules (451), recruit macrophages (452), increase thrombosis (453), and reduce vasoreactivity (454), and are positively associated with cardiovascular events (249, 455.
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ClinicalTrials.gov 02/17/2020 12:00
Its main mechanism is to inhibit thrombosis after reducing fibrinogen, and to dissolve thrombus.
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It was published in the American Heart Association's journal Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) Mice were exposed to hookah smoke from a smoking machine for an hour every day for one week in the lab.
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The introduction of the direct oral anticoagulants for stroke prevention in atrial fibrillation and the management of thromboembolism has transformed the care of patients with these disorders. These drugs, which selectively and reversibly inhibit factor Xa or thrombin in the common pathway of the coagulation cascade, have a wide therapeutic window; this allows for simplified dosing regimens without laboratory monitoring of most adult patients as contrasted to vitamin K antagonists. This class of drug is also associated with a lower bleeding risk than vitamin K antagonists, which has been most clearly demonstrated by a 50% relative risk reduction in intracranial hemorrhage. Nevertheless, bleeding with the direct oral anticoagulants remains a.
PR Newswire 12/17/2019 08:30
We're proud to support the American Heart Association's education efforts around best practices for treating this life-threatening condition," said Scott Garland , Portola's president and chief executive officer.
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