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PubMed News (NIH) 07/05/2020
Contributors : Celia Alda-Catalinas ; Danila Bredikhin ; Irene Hernando-Herraez ; Fátima Santos ; Oana Kubinyecz ; Mélanie A Eckersley-Maslin ; Oliver Stegle ; Wolf Reik Series Type : Expression profiling by high throughput sequencing Organism : Mus musculus. Zygotic genome activation (ZGA) is a crucial developmental milestone that remains poorly understood.
PubMed News (NIH) 07/05/2020
Contributors : Zhijun Han ; Kairong Cui ; Katarzyna Placek ; Ni Hong ; Wei Chen ; Keji Zhao ; Wenfei Jin Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; Other Organism : Mus musculus. While mammalian genomes are diploid, previous studies extensively investigated the average chromatin architectures without considering the differences between homologous chromosomes.
PubMed News (NIH) 07/01/2020
Contributors : Maria J Bruzzone ; David Shore Series Type : Genome binding/occupancy profiling by high throughput sequencing Organism : Saccharomyces cerevisiae. Here we show that the ChEC-Seq technique is able to differentiate the binding specificities of Esa1 and Gcn5 two chromatin-binding factors displaying widespread genome-wide associations.

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