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ENDPOINTS 09/12/2019 16:08
Investigators involved in developing a ⭐⭐⭐⭐ cancer drug tapped as a bright prospect in Amgen’s early stage oncology pipeline have halted enrollment of new patients after signs of “cardiac toxicity” at a related drug with the same mechanism raised safety concerns at the FDA, prompting a clinical hold.
ENDPOINTS 07/31/2019 05:56
Once you’ve got some buzz going for a potential breakthrough drug, it doesn’t take much more than a hint of progress to get the industry spotlight to swivel back in your direction. For Amgen , where that kind of R&D excitement has been a long time coming, their moment arrived Tuesday evening, when the pharma giant noted that they had registered widening responses for their KRAS drug AMG510, adding tumor responses in colorectal and appendiceal cancer patients after a 50% response rate among a tiny group of non-small cell lung cancer groups at ASCO. “We have completed enrollment in our monotherapy expansion cohort and are also now enrolling non-small cell lung cancer patients in the PD-1 combination arm,” added R&D chief David Reese in their

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