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ClinicalTrials.gov 10/16/2019 08:28
Participants in the chemotherapy group may cross over to treatment with TAK-788 after IRC-assessed PD is documented.
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Business Wire 10/16/2019 07:30
Eligible patients had no prior chemotherapy or radiation treatment for MPM, were at least 18 years old, had an Eastern Cooperative Oncology Group performance status of 0-1, and had at least one measurable or evaluable lesion according to the modified ...
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Purpose:. Emerging evidence indicates that gut microbiome plays a crucial role in the cancer pathogenesis. Although Fusobacterium nucleatum ( F. nucleatum ) is associated with poor prognosis in multiple cancers, its clinical significance in predicting response to chemotherapy in patients with esophageal squamous cell carcinoma (ESCC) remains unclear. Experimental Design:. The F. nucleatum levels were quantified by qPCR assays in tumor tissues from 551 patients with ESCC from two independent cohorts, including 101 patients who received neoadjuvant chemotherapy prior to curative resection. Associations between F. nucleatum burden and recurrence-free survival (RFS), as well with chemotherapeutic response were evaluated using response evaluation
More from Clinical Cancer Research - Recent Issues (abstracts):
The immune system is a robust and often untapped accomplice of many standard cancer therapies. A majority of tumors exist in a state of immune tolerance where the patient's immune system has become insensitive to the cancer cells. Because of its lymphodepleting effects, chemotherapy has the potential to break this tolerance. To investigate this, we created a mathematical modeling framework of tumor-immune dynamics. Our results suggest that optimal chemotherapy scheduling must balance two opposing objectives: maximizing tumor reduction while preserving patient immune function. Successful treatment requires therapy to operate in a “Goldilocks Window” where patient immune health is not overly compromised. By keeping therapy “just right,” we sh.
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The report provides broad industry data on the Chemotherapy Treatment market, such as size, forecasted growth, profitability, key players, market share and market trends will give you a high-level overview of Chemotherapy Treatment market opportunities.
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Technology Org 10/14/2019 03:00
New research aims to uncover role of genetics in heart damage from chemotherapy in children with Down syndrome.
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FeedNavigator (EU) 10/11/2019 08:37
Older age, type of hematologic malignancy (acute leukemia), shorter time from dental extraction to initiation of chemotherapy, low platelet count or hemoglobin level, requirement for red blood cell concentrate or platelet transfusion, and use of an absorbable hemostatic agent were statistically associated with the occurrence of delayed socket healing.
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Cancer Network 10/11/2019
A comparison of the actual outcomes for patients treated with chemotherapy plus endocrine therapy and the expected outcomes for those treated with endocrine therapy alone substantially favored the addition of chemotherapy.
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Lancet 10/10/2019 19:17
We thank Xin Yang and colleagues and Sander Bins and Ron Mathijssen for their comments regarding the KEYNOTE-040 study.1 This phase 3 trial showed a clinically meaningful improvement in overall survival1 and stable health-related quality of life2 in patients who received pembrolizumab compared with those who received the standard-of-care treatment.
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Of these patients, 149 patients treated with chemotherapy were divided into three groups as follows: neoadjuvant chemotherapy followed by IMRT (NCT) group, concurrent chemotherapy with IMRT (CCRT) group, and neoadjuvant chemotherapy followed by CCRT (NC+CCRT) group.
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PR Newswire 10/09/2019 09:00
This analysis of the CANTO cohort shows for the first time that anti-hormonal treatments do not have lesser effects than chemotherapy on women's quality of life.
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Medical Xpress - Cancer News 10/09/2019 07:28
Hormone therapy has a bigger impact than chemotherapy on quality of life in women with breast cancer.
More from Medical Xpress - Cancer News:
First, as stated in the protocol, surgery was scheduled on day 123 after beginning total neoadjuvant chemotherapy (TNT), whether the patient received CRT initially or induction chemotherapy before CRT.
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