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Medindia.com 08/10/2019 09:29
Similarly, these same mutations often are found in women who have endometriosis - a painful condition in which uterine tissue grows outside the uterus - but many of those affected never develop endometrial cancer.
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FeedNavigator (EU) 08/08/2019 10:20
Regarding the pathogenesis of endometrial cancer, the traditional view is that long-term non-progesterone estrogen overstimulation of the endometrium is the main cause of endometrial hyperplasia and endometrial cancer.
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ClinicalTrials.gov 08/08/2019 08:43
Patients then undergo standard of care hysterectomy on day 15.
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New Drug Application (NDA) is supported by data from pivotal Phase 3 studies of nearly 800 patients. Clinical trials in women with heavy menstrual bleeding (HMB) associated with uterine fibroids showed a statistically significant reduction in HMB with el...
GlobeNewswire 08/02/2019 09:15
The presentations will focus on several features of endometriosis, including genetic mechanisms underlying the disorder, potential disease gene interactions, and the mechanisms through which some benign endometriosis lesions might become cancerous.
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ecancer news 08/02/2019 04:53
Endometrial diseases, including endometrial cancer can be imitated in a lab dish.
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Human medicines European public assessment report (EPAR): Topotecan Hospira, topotecan, Uterine Cervical Neoplasms,Small Cell Lung Carcinoma, Date of authorisation: 09/06/2010, Revision: 14, Status: Authorised.
Cancer Network 07/23/2019
A phase II study found that the combination of ribociclib and letrozole showed promising activity in patients with estrogen receptor-positive ovarian cancer and endometrial cancer.
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PubMed News (NIH) 07/15/2019
Contributors : Viviana Annibali ; Simona Giglio ; Stefano Volinia Series Type : Non-coding RNA profiling by array Organism : Homo sapiens ; synthetic construct. in the current study we identified a miRNAs signature able to discriminate between typical and atypical endometrial hyperplasia the identification of molecular marker that can differentiate between these two distinct pathological conditions is highly considered to be useful for the clinical management of the patients, owing to the fact that hyperplasia with atypical change is associated with higher risk of develop cancer.
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Benzinga 07/08/2019 01:00
Through strategic in-licensing and disciplined drug development, ObsEva has established a late-stage clinical pipeline with development programs focused on treating endometriosis, uterine fibroids, preterm labor and improving IVF outcomes.
Accordingly, our patient has morphological evidence to support the endometriotic origin by exhibiting the continuity between mucinous carcinoma and the endometriosis, and the presence of multifocal atypical epithelium in the endometriotic cyst.
More from Diagnostic Pathology - Abstract:
Patients with the grade 3 endometrial cancer (EC) have a generally poor prognosis, and the specific role of circRNAs in the grade 3 EC remains unclear.
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