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PubMed News (NIH) 07/01/2019
Contributors : Jesus Gonzalez-Bosquet ; Henry D Reyes ; Eric Devor Series Type : Methylation profiling by genome tiling array Organism : Homo sapiens. Introduction/ Background: The epigenome represents and adds another facet of complexity to cancer that needs to be understood to categorize patients into those at risk of disease, recurrence, or treatment failure.
PubMed News (NIH) 07/01/2019
We have previously shown that CTCFL (also known as BORIS, Brother of the Regulator of Imprinted Sites) is expressed in a large proportion of ovarian cancers, which is associated with global and promoter-specific DNA hypomethylation, advanced tumor stage, and poor prognosis.
PubMed News (NIH) 06/07/2019
Contributors : Mengnan Zhang ; Neda Jabbari ; Minati Satpathy ; Lilya V Matyunina ; Yuehua Wang ; Lila D McDonald ; John F McDonald Series Type : Expression profiling by array Organism : Homo sapiens. Epithelial-to-mesenchymal transition (EMT) and mesenchymal-to-epithelial transition (MET) are reciprocal molecular processes essential in early embryonic development that have been co-opted by cancer cells to facilitate tumor metastasis.

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