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Oral Diseases 10/20/2019 12:18
Abstract. Background. Buccal mucosal squamous cell carcinoma (BMSCC) is an aggressive oral cancer. Moreover, reversion‐inducing cysteine‐rich protein with Kazal motifs (RECK) is a well‐known tumor suppressor in many cancers. Our aim was to investigate the association of RECK expression with prognosis in BMSCC patients with different clinicopathological features. Materials and Methods. The expression level of RECK was determined by immunohistochemistry using tissue microarrays containing specimens from 193 BMSCC patients. The association of RECK expression with outcomes in BMSCC patients stratified by different clinicopathological features was analyzed by Cox proportional hazards models. Results. The low expression level of RECK was associated w.
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PubMed News (NIH) 10/20/2019
Contributor : Margit Balázs Series Type : Expression profiling by array Organism : Homo sapiens. Melanoma cell lines were established and used for Affymetrix Human Gene 1.0 ST Array.
More from PubMed News (NIH): 10/18/2019 07:30
Condition : Lung Squamous Cell Carcinoma Intervention : Drug: Afatinib Sponsor : Shanghai Chest Hospital Recruiting.
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Business Wire 10/18/2019 07:00
The DecisionDx-Melanoma test has been previously validated to guide SLNB decisions, as patients with T1-T2 melanoma (tumor depth of 2 mm or less) with a Class 1A result had very low rates of SLN positivity.
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Channel NewsAsia (Singapore) 10/18/2019 06:07
According to experts, many people aren’t aware that just five sunburns can double one’s chances of developing melanoma, the most common life-threatening form of skin cancer.
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Healio News 10/17/2019 13:51
Adjuvant whole-brain radiotherapy ‘should not be recommended’ for certain patients with melanoma brain metastases.
More from Healio News: 10/17/2019 13:22
Wistar receives major NIH grant to advance research on new melanoma targeted therapies.
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FeedNavigator (EU) 10/17/2019 07:53
Eur J Dent. 2019 Oct 16. doi: 10.1055/s-0039-1698368. [Epub ahead of print]
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Cancer Network 10/17/2019
Study Moves the Needle for Melanoma Patients with Rare BRAF Mutations.
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Long Non-Coding RNA LINC00152 Regulates Cell Proliferation, Migration And Invasion In Esophageal Squamous Cell Carcinoma Via miR-107/Rab10 Axis.
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EurekAlert 10/16/2019
HPV-driven cancers such as head and neck squamous cell cancers show an overexpression of GLUT1 but the relationship between HPV and the GLUT1 transporter has never been explored in ASCC.
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GlobeNewswire 10/15/2019 08:00
Immutep Reports Positive Final Efficacy Data from TACTI-mel Trial in Melanoma Nasdaq:IMMP.
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Orphan designation: Sindbis virus envelope pseudotyped lentiviral vector encoding New York oesophageal squamous cell carcinoma-1 protein, Treatment of soft tissue sarcoma, 21/03/2016, Withdrawn.
More from European Medicines Agency - EMEA (EU):
Purpose:. Emerging evidence indicates that gut microbiome plays a crucial role in the cancer pathogenesis. Although Fusobacterium nucleatum ( F. nucleatum ) is associated with poor prognosis in multiple cancers, its clinical significance in predicting response to chemotherapy in patients with esophageal squamous cell carcinoma (ESCC) remains unclear. Experimental Design:. The F. nucleatum levels were quantified by qPCR assays in tumor tissues from 551 patients with ESCC from two independent cohorts, including 101 patients who received neoadjuvant chemotherapy prior to curative resection. Associations between F. nucleatum burden and recurrence-free survival (RFS), as well with chemotherapeutic response were evaluated using response evaluation
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