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lncRNA LEF1-AS1 Promotes Proliferation and Induces Apoptosis of Non-Small-Cell Lung Cancer Cells by Regulating miR-221/PTEN Signaling.
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ClinicalTrials.gov 05/22/2020 19:23
Condition : Non Small Cell Lung Cancer Intervention : Drug: TQ-B3139 Sponsor : Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Not yet recruiting.
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Reuters.com 05/22/2020 16:40
Takeda Pharmaceutical Co Ltd:
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FP Trading Desk (Canada) 05/22/2020 16:30
− Long-Term Results from the Phase 3 ALTA 1L Trial Established ALUNBRIG as a Superior First-Line Treatment Compared to Crizotinib for People with ALK+ Metastatic NSCLC, Including those with Brain Metastases CAMBRIDGE, Mass. & OSAKA, Japan — Takeda Pharmaceutical Company Limited (TSE:4502/NYSE:TAK) today announced that the U.S. Food and Drug Administration (FDA) approved ALUNBRIG (brigatinib) [...]
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European Respiratory Journal 05/22/2020 09:03
Purpose. HIV infection is an exclusion criterion in lung cancer trials. This multicenter phase II trial aimed to assess feasibility, efficacy and safety of first-line carboplatin plus pemetrexed (CaP) followed by pemetrexed ℗ maintenance in people living with HIV (PLHIV) with advanced non-squamous non-small cell lung cancer (NS-NSCLC). Methods. Four cycles of CaP were followed by P-maintenance therapy in patients with Eastern Cooperative Oncology Group performance status (PS) ≤2. The primary objective was a disease control rate (DCR) ≥30% after 12 weeks. Results. Of the 61 PLHIV enrolled 49 (80%) had a PS 0–1, 19 (31%) brain metastases. Median CD4 lymphocyte count was 418 cells·µL –1 (range: 18–1230), median CD4 lymphocyte nadir 169.5 cells·µL.
Cancer Network 05/22/2020
In order to address the knowledge gap, the International Association for the Study of Lung Cancer (IASLC) conducted an international survey to assess current practices and possible barriers to molecular testing.
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Onclive 05/19/2020 11:46
Jamie E. Chaft, MD, provides insight into IRAEs and immunotherapy restart, considerations for immunotherapy in the pre- and post-operative period, outlines biomarker research in lung cancer, and projects her hopes for the future use of this approach in this space.
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GlobeNewswire 05/19/2020 01:00
FDA approves Roche’s Tecentriq as a first-line monotherapy for certain people with metastatic non-small cell lung cancer Swiss Stock Exchange:RO.
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Therefore, it can be speculated that colorectal cancer is more likely to metastasize to the lung than breast cancer, and breast cancer is more likely to metastasize to the lung in the Chinese population than in others.
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Cancer Cell International 05/18/2020 20:00
Microarray profiles reveal that circular RNA hsa_circ_0007385 functions as an oncogene in non-small cell lung cancer tumorigenesis.
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Healio News 05/18/2020 17:32
FDA expands Tecentriq approval for metastatic lung cancer.
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The US Food and Drug Administration (FDA) approved the combination of nivolumab plus ipilimumab as a first-line treatment for patients with certain lung cancers.
More from RT: For Decision Makers in Respiratory Care:
People with lung conditions 'should NOT wear face masks if it makes it hard to breathe'.
More from Mail on Sunday (United Kingdom):
Business Wire 05/18/2020 15:30
About lung cancer According to the American Cancer Society, it is estimated that more than 228,000 Americans will be diagnosed with lung cancer in 2020, and NSCLC accounts for 80-85% of all lung cancers.
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PubMed News (NIH) 05/18/2020
Status Public on May 18, 2020 Title FAM111B contributes to the growth of lung adenocarcinoma with KRAS mutation by degrading p16 and promoting cell cycle.
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