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EurekAlert 08/22/2019
Risk factors for liver cancer include chronic hepatitis A or B infection that can result in a scarring of the liver called cirrhosis, which increases liver cancer risk, as well as alcohol abuse, smoking and, increasingly in this country, non ...
More from EurekAlert: 08/21/2019 14:27
Related: Ginseng phytonutrient Ginsenoside Rg3 effective against hepatocellular carcinoma.
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Author provided This misses an opportunity to diagnose and treat liver disease at an early stage.
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DoctorsLounge 08/20/2019 13:00
Lipophilic statin use is associated with significantly reduced hepatocellular carcinoma incidence and mortality in adults with chronic viral hepatitis, according to a study published online Aug. 20 in the Annals of Internal Medicine.
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PubMed News (NIH) 08/20/2019
Contributors : Yu Wang ; Kam M Hui Series Type : Other Organism : Homo sapiens. We performed genome-wide functional knockout screens using GECKOv2 library to identify essential growth targets in two hepatocellular carcinoma (HCC) cell lines, HCCLM3 and SNU449.
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These findings suggest that chelidonine restricted the EMT in HCC cells.
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Healio News 08/17/2019 16:27
Models calculate risk for post-hepatectomy liver failure in cirrhosis.
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FeedNavigator (EU) 08/17/2019 06:48
NAFLD can cause liver inflammation and progress to Non-Alcoholic Steatohepatitis (NASH), fibrosis, cirrhosis or Hepatocellular Cancer (HCC.
More from FeedNavigator (EU): 08/16/2019 07:07
This has been demonstrated in mouse models where the fat inflammatory cells contributed to liver inflammation and worsened liver damage, emphasising the importance of the relationship between fat tissue and the liver in NAFLD.
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Tumor-associated macrophages (TAM) play pivotal roles in tumor progression and metastasis, but the contribution and regulation of different macrophage populations remain unclear. Here we show that Notch signaling plays distinct roles in regulating different TAM subsets in hepatocellular carcinoma (HCC). Myeloid-specific NOTCH blockade by conditional disruption of recombination signal binding protein Jκ (RBPj cKO) significantly delayed the growth of subcutaneously inoculated Lewis lung carcinoma (LLC), but accelerated orthotopically inoculated hepatic Hepa1-6 tumors in mice. In contrast to subcutaneous LLC, RBPj cKO significantly increased the number of TAMs in hepatic Hepa1-6 tumors despite impeded differentiation of monocyte-derived TAMs (
More from Cancer Research - Recent Issues (abstracts): 08/10/2019 19:50
A new study from the UT Southwestern Simmons Comprehensive Cancer Center demonstrates that antiviral drugs for hepatitis C reduce liver-related deaths by nearly 50% in patients with a history of liver cancer.
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