Millie: Search Results

There are two main categories—bone marrow transplants and cord blood transplants—both of which involve replacing diseased blood cells with healthy ones.

Further, pre-clinical data suggests HDAC inhibition could also increase CD33 expression in myeloid leukemia cells, thereby allowing for increased GO binding to AML blasts.

Condition : Acute Myeloid Leukemia Interventions : Drug: Idasanutlin; Drug: Cytarabine; Drug: Daunorubicin; Procedure: Allogeneic Hematopoietic Stem Cell Transplant (Allo-HSCT) Sponsor : Hoffmann-La Roche Not yet recruiting.

Patients with childhood leukemia — ie, a diagnosis of leukemia before age 20 — between 1970 and 2008 included in the cancer database were matched with a comparison cohort of 5 contemporary patients without a leukemia diagnosis in childhood.

Cancer biopharma firm Xencor has revealed it is to place a hold on its ongoing Phase 1 trial of XmAb14045, its investigational CD123 x CD3 bispecific antibody, in patients with relapsed or refractory acute myeloid leukaemia and other CD123-expressing hematologic malignancies after the deaths of two patients which are considered to be "at least possibly related" to the use of the drug. The deaths were originally detailed in a safety report submitted by Xencor to the FDA. read more.

The World Health Organization has warned consumers to be on vigil against fake versions of leukemia drug Iclusig sold in Europe and the Americas.

Used together, Bio-Rad’s system and kit can precisely and reproducibly monitor molecular response to treatment in patients with chronic myeloid leukemia (CML.

After two deaths, FDA hits the brakes on leukemia treatment study.

Two deaths in a clinical trial of a drug for acute myeloid leukemia have prompted the Food and Drug Administration to impose a partial clinical hold on the study.

The product generated revenues of $2 billion for BMS in 2018, and just recently, it nabbed expanded FDA approval as a first-line treatment for children with a form of acute lymphoblastic leukemia.

Condition : Chronic Lymphocytic Leukemia Intervention : Drug: BR as Maintenance Sponsor : Pirogov Russian National Research Medical University Active, not recruiting.

CAMBRIDGE, Mass., Feb. 20, 2019 (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (NASDAQ:AGIO), a leader in the field of cellular metabolism to treat cancer and rare genetic diseases, today announced that the U.S. Food and Drug Administration (FDA) has accepted the company's supplemental New Drug Application (sNDA) for TIBSOVO® (ivosidenib) for the treatment of patients with newly diagnosed acute myeloid leukemia (AML) with an isocitrate dehydrogenase 1 (IDH1) mutation who are not eligible for standard therapy.

Deaths spur partial hold for Xencor’s CD3 bispecific for leukemia, partnered with Novartis in $2.5B deal – Endpoints News.

Undifferentiated blast cells proliferate in the bone marrow rather than mature into normal blood cells.

After finally being diagnosed with blood cancer, things took a dramatic turn for the worse when Ms Lora-Cabán began coughing up blood.

She found out firsthand how important it is for blood to be on the shelf for those in need after she was diagnosed with acute myeloid leukemia 10 years ago.

This meeting brings together experts from across the globe to discuss new advances in the treatment of blood-related diseases, including cancers of the blood and bone marrow.

Conditions : Acute Myeloid Leukemia; AML Interventions : Drug: Palcociclib; Drug: CPX-351 Sponsor : Aziz Nazha Not yet recruiting.

Pediatric ALL occurs when the bone marrow makes too many immature lymphocytes, which are a type of white blood cell.

Blood and bone marrow cancers, such as leukemia, grow in the bone marrow and don't allow normal blood cells to develop.

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