An antibody-based treatment can gently and effectively eliminate diseased blood-forming stem cells in the bonemarrow to prepare for the transplantation of healthy stem cells, according to a study in mice by researchers at the Stanford University School of Medicine.
The first results in chronic lymphocytic leukemia are promising, and I am convinced that our method will help develop personalized therapies for leukemia and other cancers.
Study led by St. Jude Children’s Research Hospital found treatment guided by measuring minimal residual disease was associated with better outcomes for hypodiploid acute lymphoblastic leukemia patients Credit: St. Jude Children’s Research Hospital Checking for minimal residual disease early in treatment can help some young high-risk leukemia patients avoid bonemarrow transplantation without compromising their [...]
Research reveals new blood cell mechanism which drives leukaemia growth Credit: University of Sussex A mechanism which drives leukaemia cell growth has been discovered by researchers at the University of Sussex, who believe their findings could help to inform new strategies when it comes to treating the cancer.
Researchers used integrated genomic analysis, including RNA sequencing, to define the genomic landscape of B-cell acute lymphoblastic leukemia (B-ALL) in almost 2,000 children and adults.
Results of landmark study published in the New England Journal of Medicine MAYWOOD, IL – A landmark study co-authored by a Loyola Medicine oncologist has found that a newer targeted drug is significantly more effective than standard therapy for treating elderly patients with chronic lymphocytic leukemia (CLL).
Fourth study published over two-year span that analyzes key leukemia protein Credit: Northwestern University CHICAGO — Northwestern Medicine scientists have discovered two successful therapies that slowed the progression of pediatric leukemia in mice, according to three studies published over the last two years in the journal Cell, and the final paper published Dec. 20 in [...]
Scientists at the Wellcome Sanger Institute, University of Cambridge, University of Nottingham and their collaborators have found that this compound, which targets an essential cancer gene, could kill leukaemia cells without harming non-leukemic blood cells.
Rapid drug response screening for leukemia stem cells offers clues to relapse and to improving patient-specific therapies Credit: Alice C, Gray Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML).
Researchers had shown that the ZNF384 fusion proteins cause leukemia when expressed in mouse bonemarrow, and that the fusions are first acquired in primitive human blood stem cells.
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