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Pharmafile 06/05/2019 06:49
AbbVie was one of many companies to present new data at this year’s American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, focusing specifically on its B-cell lymphoma-2 (BCL-2) inhibitor Venclyxto (venetoclax) in combination with obinutuzumab in the treatment of previously untreated chronic lymphocytic leukaemia (CLL). In the first randomised trial to investigate stopping an oral-based, chemotherapy-free combination after 12 months in the disease, it was found that the drug combo, which AbbVie is jointly developing with Roche, achieved superior rates of progressio. read more.
Pharmafile 05/16/2019 05:19
Venclexta (venetoclax), the oral B-cell lymphoma-2 (BCL-2) inhibitor co-developed by AbbVie and Roche, has been approved by the FDA in combination with Gazyva (obinutuzumab) for the treatment of chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) in patients who have not received prior treatment. The US agency reached the decision in just two months through the Breakthrough Therapy pathway, based on the data which indicated that the combo "demonstrated superior progression-free-survival (PFS)", as assessed by an independent review committee. read more.

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