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News-Medical.net 08/06/2020 00:31
Our research lays the groundwork for a clinical trial that could lead to new, life-saving treatment options for breast cancer patients that do not respond to conventional immunotherapies.
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The present study assesses the correlation between X-ray repair cross-complementing group 3 (XRCC3) polymorphism with breast cancer and treatment response in Egyptian female breast cancer patients.
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Forbes 08/05/2020 12:45
Joining Forces To Fight Breast Cancer Liyfe Clinic In addition to its virtual service, Liyfe told me that it is going to partner with two other YC graduates that also focus on breast cancer.
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ClinicalTrials.gov 08/05/2020 07:26
Condition : HER2-negative Breast Cancer Interventions : Drug: AT regimen; Drug: TP regimen Sponsor : Sichuan Provincial People's Hospital Not yet recruiting.
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Korean Biomedical Review 08/05/2020 04:01
Song added that Pfizer Korea would continue to make efforts to present improved treatment options to patients and medical staff and bring meaningful changes to patients' lives through innovative treatments for breast cancer and various carcinomas.
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Medindia.com 08/05/2020 02:37
However, despite the possibilities opened to medical specialists by MRI, this method is rarely used to produce breast scans because apart from the scanner itself, this procedure requires additional specialized equipment.
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PharmiWeb.com 08/05/2020 00:38
Breast Biopsy refers to a diagnostic procedure to determine whether a small sample removed from the breast tissue is cancerous.
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PubMed News (NIH) 08/05/2020
Contributors : Ngoc Bui ; Sean Yoda ; Jiqiang Yao ; Laura Hall ; Tania Mesa Series Type : Other Organism : Homo sapiens. Upon treatment of TGFβ in MCF10DCIS cells, there are 76 up-regulated and 1 down-regulated microRNAs identified.
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HER2‐positive breast cancer represents aggressive subtype typical of poor response to standard chemotherapy.
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Healio News 08/04/2020 11:42
Back to Healio Pregnancy after breast cancer appeared safe for women with germline BRCA mutations and did not appear to worsen maternal prognosis, according to results of a retrospective study published in Journal of Clinical Oncology.
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Business Wire 08/04/2020 09:00
The pivotal study evaluated the safety and efficacy of pegloprastide in women with primary, nonrecurrent breast cancer undergoing surgery.
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The molecular processes fueling disease progression have been delineated in recent studies and the clonal composition of breast cancer samples can be examined in detail.
More from Cancer Research - Recent Issues (abstracts):
The Crk adaptor protein, a critical modifier of multiple signaling pathways, is overexpressed in many cancers where it contributes to tumor progression and metastasis. Recently, we have shown that Crk interacts with the peptidyl prolyl cis-trans isomerase, Cyclophilin A (CypA; PP1A) via a G 219 P 220 Y 221 (GPY) motif in the carboxyl-terminal linker region of Crk, thereby delaying pY221 phosphorylation and preventing downregulation of Crk signaling. Here, we investigate the physiologic significance of the CypA/Crk interaction and query whether CypA inhibition affects Crk signaling in vitro and in vivo . We show that CypA, when induced under conditions of hypoxia, regulates Crk pY221 phosphorylation and signaling in cancer cell lines. Using
More from Molecular Cancer Research - Recent Issues (abstracts):
HER2-positive breast cancer is currently managed with chemotherapy in combination with specific anti-HER2 therapies, including trastuzumab. However, a high percentage of patients with HER2-positive tumors do not respond to trastuzumab (primary resistance) or either recur (acquired resistance), mostly due to molecular alterations in the tumor that are either unknown or undetermined in clinical practice. Those alterations may cause the tumor to be refractory to treatment with trastuzumab, promoting tumor proliferation and metastasis. Using continued exposure of a HER2-positive cell line to trastuzumab, we generated a model of acquired resistance characterized by increased expression of several cytokines. Differential gene expression analysis
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Benzinga 08/03/2020 10:25
Her services include the evaluation of both benign conditions and breast cancer.
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Medical Xpress - Cancer News 08/03/2020 07:30
Breast cancers, inclusive of ductal carcinoma in situ, were identified from the completed BMTSS survey.
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Translational Relevance Early identification of the AKT1E17K genomic biomarker, coupled with a novel targeted and nonmyeloablative agent, could enhance treatment options in AKT1E17K-mutant estrogen receptor–positive (ER+) metastatic breast cancer.
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