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LabOnline (Australia) 06/25/2019 10:00
BioTek Instruments enhances cell biology workflows with the introduction of the Scratch Assay Starter Kit for use with its Lionheart Automated Cell Imagers and Cytation Cell Imaging Multi-Mode Readers. The starter kit includes the AutoScratch Wound Making Tool, Scratch App software, sample packages of 24- and 96-well microplates, and cleaning reagents. When using the kit in kinetic cell migration and invasion scratch wound assays, AutoScratch automatically creates repeatable scratches of equivalent size and area in confluent cell monolayers to increase consistency and facilitate normalisation across subsequent assays. Interchangeable manifolds facilitate processing in 24- and 96-well microplates, and AutoScratch easily fits into laminar flo.
LabOnline (Australia) 06/25/2019 10:00
For pharmaceutical and food productions, continuous control of ingredients is indispensable. Usually, this would be done by sampling and a laboratory analysis via chromatography or spectrometers. However, such a process is time-consuming and allows only for spot checks. At Fraunhofer IAF, researchers have developed a measuring system capable of quality control in real time, identifying even the smallest amounts of substances based on their molecular composition. Real-time measurements with quantum cascade lasers. The core of the system is an extremely fast tunable quantum cascade laser (QCL) operating in the mid-infrared range. Based on backscattering spectroscopy, the laser system not only identifies small amounts of chemical substances in
LabOnline (Australia) 06/25/2019 10:00
Seeking new treatments to slow the progression of Alzheimer’s disease, European researchers have found the blood pressure drug nilvadipine increased blood flow to the brain’s memory and learning centre among people with Alzheimer’s disease without affecting other parts of the brain. Published in the journal Hypertension , the findings indicate that the known decrease in cerebral blood flow in patients with Alzheimer’s can be reversed in some regions.
LabOnline (Australia) 06/24/2019 10:00
The BioCAM DupleX, from 3Brain, is a fully bidirectional microelectrode array (also known as a multi-electrode array/MEA) platform for 2D and 3D in vitro electrophysiology. Powerful for in vitro functional imaging, its bidirectional capabilities allow researchers to simultaneously record high-density electrophysiological data at 18 kHz and induce electrical stimulation at any of the 4096 microelectrodes.
LabOnline (Australia) 06/24/2019 10:00
An international trial into the treatment of chronic lymphocytic leukaemia (CLL) has been so successful that the US FDA approved the treatment for patients with the disease prior to the trial data being presented. With contributions from centres in Australia, New Zealand, the UK, Russia, Italy, the US and Bulgaria, the Phase 3 trial involved 432 patients with CLL, the most common form of leukaemia.
LabOnline (Australia) 06/24/2019 10:00
Microba , an Australian biotech company specialising in gut microbiome analysis, has received a $4.1 million investment from global precision medicine company Macrogen . The strategic investment provides a platform for Microba to scale rapidly and, working together, the parties intend to secure the position of Microba as the leading microbiome testing company on a global scale.
LabOnline (Australia) 06/23/2019 10:00
Japanese researchers are looking to develop a novel treatment for the millions of people who suffer from Parkinson’s disease (PD) — a neurodegenerative disease that can strike at any age, though it is most common in those aged over 60. While not fatal in and of itself, the progressive neurodegeneration that is characteristic of PD can often cause secondary effects that lead to death — so the new research, published in the journal Scientific Reports , provides a ray of hope for patients. The exact cause of PD is still a mystery, but researchers believe that both genetics and the environment are likely to play a part. Importantly, though, all PD patients show a loss of dopaminergic neurons in the brain and increased levels of a protein called.
LabOnline (Australia) 06/23/2019 10:00
Cranberries are highly sought after for their tangy taste and the antioxidants they contain, but a new study from Canadian researchers provides evidence that they could also help in the fight against antibiotic resistance. Due to the overuse of antibiotics in medicine and agriculture, we are on the cusp of returning to a pre-antibiotic era in which minor infections can once again become deadly.
LabOnline (Australia) 06/23/2019 10:00
Tecan has introduced a redesigned packaging format for its Tecan Pure liquid handling (LiHa) disposable clear tips. The more compact and lightweight packaging option has less dead space between tip racks, making it easier and more economical to transport, as well as reducing waste disposal costs. By optimising the packaging, the product now contains 45% less plastic than the current Tecan Pure blister packs, supporting progress towards a more sustainable approach. The updated design — initially available for the 200 and 1000 μL Tecan Pure clear tips — makes tips easier to store, maximising use of laboratory space. The clear LiHa disposable tips range provides verified performance for a variety of pipetting activities that do not require cap.
LabOnline (Australia) 06/23/2019 10:00
ERACHECK ECO, from Eralytics, is a dual-beam, non-dispersive IR spectrometer enabling eco-efficient measurement of oil in water based on the CFC-free solvent cyclohexane. Total petroleum hydrocarbons (TPH) and total oil and grease (TOG) in water and soil are measured with sub-ppm precision and the IR analyser is fully compliant with the latest oil-in-water standard ASTM D8193. Unlike gravimetric methods, ASTM D8193 does not require evaporation of the solvent, eliminating the risk of light ends getting lost during the measurements. Compared to GC methods that do not detect fractions eluting outside the defined time window, ASTM D8193 enables a faster, easier and more complete fraction of extracted hydrocarbons, according to the company. The
LabOnline (Australia) 06/20/2019 10:00
Western Australian researchers have used rigorous contamination controls to confirm that exposure to bacteria begins in the womb, laying to rest the longstanding question of whether or not the womb is sterile. Their work has been published in the journal Frontiers in Microbiology . “Over the last decade, numerous studies have detected bacterial DNA in amniotic fluid and first-pass meconium [baby’s first poo], challenging the long-held assumption that the womb is sterile,” said lead author Dr Lisa Stinson, from The University of Western Australia (UWA). “However, some argue that the results are false positives — contaminants in the reagents used in DNA analysis.”To settle the issue, Dr Stinson and colleagues collected amniotic fluid samples.
LabOnline (Australia) 06/20/2019 10:00
Harvard Apparatus’ preconfigured small animal anaesthesia systems are complete, easy to use, versatile and compact. They have three independent quick-connect gas outputs to allow halogenated gas to be distributed to one, two or three anaesthetic devices, such as a mask, induction box, etc, so there is no manifold required. The product is designed for mice, rats and other small animals under 4.5 kg. It is available in a tabletop or mobile set-up, with a choice of active or passive scavenging systems. Harvard Apparatus also provides individual anaesthesia and surgical components and can assist in creating custom systems.
LabOnline (Australia) 06/20/2019 10:00
Melbourne-based company Australian Pharmaceutical Manufacturers (APM), a division of Pact Group , has opened expanded operations in the suburb of Keysborough, allowing the company to increase exports and create 44 new local jobs. With support from the Victorian Government, the $6.9 million upgrade will allow APM, which offers contract manufacturing and packaging services for products including vitamin and mineral supplements, to take on more work from existing clients and increase its reach across Asia. “The Victorian Government is busy walking the talk, actually investing in supporting manufacturing and breathing life into projects that grow employment and help Victorian business succeed,” said Pact Group Chairman Raphael Geminder. “We all.
LabOnline (Australia) 06/19/2019 10:00
The XPERT TOC/TN b analyser, from Trace Elemental Instruments, is a robust, all-in-one elemental combustion analyser that measures total organic carbon and total bound nitrogen concentrations simultaneously from a single injection. The all-in-one benchtop unit is suitable for the laboratory analysis of TOC and TN b in water and soil samples, in medium- to high-throughput environmental laboratories.
LabOnline (Australia) 06/19/2019 10:00
US scientists have added a ‘homing beacon’ to tumours, in the form of an injectable hydrogel, that attracts chemotherapy medicines towards cancer cells while sparing their normal counterparts. The treatment has been tested in mice and described in the journal ACS Central Science . Scientists have previously tried to target chemotherapy drugs to tumours by attaching antibodies that bind to proteins expressed on the cancer cells’ surfaces; however, less than 1% of the administered drug actually ends up at the tumour site. Matthew Webber and his colleagues at the University of Notre Dame decided to take a different approach: using cucurbituril to target therapies to a tumour. Cucurbituril is a pumpkin-shaped molecule that can capture certain c.
LabOnline (Australia) 06/18/2019 10:00
Motor neurone disease (MND), also known as amyotrophic lateral sclerosis (ALS), is a progressive, fatal neurodegenerative disease that kills those cells in the central nervous system that convey signals from the brain to muscles throughout the body. This results in muscle weakness, paralysis and death, typically of respiratory failure, within three years of diagnosis. Peak age of onset is roughly 60 years, but the disease can affect people both older and younger than this. “If you are unfortunate enough to be diagnosed with motor neurone disease, you have a tough time ahead of you,” said Associate Professor Peter Crouch from the University of Melbourne . “Your ability to breathe, your ability to swallow, your ability to speak, your ability

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