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Healio News 02/25/2020 06:00
Using electronic health records, researchers showed that connection through health care workers to patients colonized with vancomycin-resistant enterococci, or VRE, is a significant risk factor for VRE acquisition among uncolonized patients. “Health care workers have a lot of contact with patients and are considered an important source of transmission, yet there [are] limited data on how these workers connect [with] patients,” Eili Y. Klein, PhD, assistant professor of emergency medicine at the Johns Hopkins University School of Medicine, told Healio. “Models of health care.
Healio News 02/24/2020 17:30
A multicenter, real-world, observational study showed safety and efficacy of a fixed-dose combination of preservative-free tafluprost and timolol in clinical practice. Patients who did not sufficiently respond to previous therapies achieved significant IOP reduction at 6 months, with the added benefit of decreased ocular surface side effects. The VISIONARY study included 577 patients with open-angle glaucoma or ocular hypertension who did not respond or were not tolerant to monotherapy with beta-blockers or prostaglandin analogues. Patients were switched to single daily administration of the.
Healio News 02/24/2020 15:50
An individualized treatment rule may increase the treatment success rate of patients with first-episode schizophrenia, according to study results published in JAMA Network Open. However, researchers noted the necessity of a clinical trial and replication of these results with an expanded predictor set before clinical implementation. “Numerous clinical trials and observational studies have investigated comparative treatment effects and risk profiles of antipsychotic drugs,” Chi-Shin Wu, MD, PhD, of the department of psychiatry at National Taiwan University, and colleagues wrote. “Others.
Healio News 02/24/2020 15:35
Patients who underwent coronary revascularization with a bioresorbable polymer sirolimus-eluting stent had significantly lower rates of target vessel MI, late/very late stent thrombosis and clinically driven target lesion revascularization compared with those who underwent the procedure with a durable polymer everolimus-eluting stent, according to 3-year data from the BIOFLOW V trial presented at Cardiovascular Research Technologies.
Healio News 02/24/2020 15:16
Nonmydriatic fundus photography after suspected minor stroke or transient ischemic attack was able to differentiate between actual stroke and mimics, according to findings from the FOTO-ED TIA study presented at the International Stroke Conference. Any retinal microvascular finding assessed with nonmydriatic fundus photography after suspected minor stroke or TIA, which can be done by nonophthalmic experts and requires no pupillary dilation, was linked to a 15.6% (95% CI, 4.2-27.1) increase in cerebrovascular event probability. Moreover, after excluding patients with lesions confirmed by.
Healio News 02/24/2020 15:00
Combining liraglutide with intensive behavioral therapy at primary care sites led to more weight loss for adults with obesity than behavioral therapy alone, according to findings published in Obesity. “There’s been a great deal of discussion about what primary care physicians should do to try to help patients with overweight and obesity,” Thomas A. Wadden, PhD, professor of psychology in the department of psychiatry at the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, told Healio. “The study comes on the heels of the Centers for Medicare.
Healio News 02/24/2020 14:30
Drug-drug interactions, or DDIs, affect about 40% of patients with hepatitis C virus being treated with direct-acting antivirals, or DAAs, according to a study published in Open Forum Infectious Diseases. Researchers said lower DDI potential among modern DAA regimens is counteracted by changing patient characteristics. “Despite the large improvements in the field of HCV therapy, DDIs are still relevant,” Benjamin Maasoumy, MD, clinical physician in the department of gastroenterology, hepatology and endocrinology at Hannover Medical School and the German Center for Infection.
Healio News 02/24/2020 13:33
Patients with chronic kidney disease who were not given pre-hydration prior to undergoing contrast-enhanced CT experienced outcomes similar to those who were given sodium bicarbonate pre-hydration, according to study results. This led researchers to conclude withholding pre-hydration is safe, as well as cost-effective. “Although hydration protocols to prevent [post-contrast AKI] PC-AKI have been implemented in daily clinical practice for more than a decade, there is a lack of evidence for the effectiveness of these costly measures, and the magnitude of possible adverse effects, including.
Healio News 02/24/2020 13:22
Rate of recovery and length of stay in skilled nursing facilities and inpatient rehabilitation facilities correlated with mobility and self-care results at discharge in patients who underwent hip fracture surgery, according to study results. “Some patients may be better served by having more time in rehab to recover and a less intensive therapy regimen after surgery for hip fracture,” Alison M. Cogan, PhD, OTR/L, told Healio Orthopedics. “We have more work to do to identify the patients who are most likely to benefit from more intensive therapy and if specific interventions.
Healio News 02/24/2020 12:40
Just 12% of adolescents with HIV aged between 12 and 24 years achieved viral suppression within 5 months after initiating ART, making them far less likely than adults to reduce their viral loads to undetectable levels, researchers reported. According to a study by Bill G. Kapogiannis, MD, a pediatric infectious disease specialist at the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and colleagues, adolescents achieved lower rates of viral suppression despite being linked to care at similar rates as adults. The researchers found that youths who were referred.
Healio News 02/24/2020 11:54
The Journal of the American Heart Association retracted a study that concluded patients who actively smoked electronic cigarettes had an increased risk for MI. It was the top story in cardiology last week. Another top story was about study that showed healthy women with long-term changes in plasma trimethylamine N-oxide had an increased risk for coronary heart disease (CHD). Read these and more news in cardiology below: Paper on e-cigarette use and MI risk retracted A study published in the Journal of the American Heart Association in June 2019 concluding that patients who smoked electronic.
Healio News 02/24/2020 11:14
Acid-suppression medication may increase the odds for colonization by multidrug-resistant microorganisms, according to a meta-analysis published in JAMA Internal Medicine. Roel P.J. Willems, MD, of the department of medical microbiology and infection at Amsterdam UMC, and colleagues wrote that use of acid suppressors is on the rise, with proton pump inhibitor use alone doubling in the United States between 1999 and 2012. This has led to concerns about how these drugs alter the gut microbiome. “Whether acid suppression facilitates colonization and infection with [multidrug-resistant.
Healio News 02/24/2020 11:14
The FDA approved the GLP-1 receptor agonist dulaglutide for the reduction of major adverse cardiovascular events for adults with type 2 diabetes who have established cardiovascular disease or multiple CV risk factors, making it the first type 2 diabetes drug approved for primary and secondary prevention populations, according to a press release from Eli Lilly.

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