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PubMed News (NIH) 10/20/2019
Contributors : Y Li ; F Huang ; S Zhang Series Type : Expression profiling by high throughput sequencing Organism : Homo sapiens. Glucose metabolism makes contributions to the development of pancreatic ductal adenocarcinoma (PDAC). Meanwhile, circular RNAs, a subset of noncoding RNAs, plays an important role in glucose metabolism and cancer progression. Analysis of low-glucose-treated and normal-glucose-treated MIA PaCa-2 cells from 6 samples (3 samples each group) was conducted. Results indicate insight into molecular signature of the pathogenesis of PDAC in abberant glucose metabolism.
PubMed News (NIH) 10/20/2019
Contributors : Syed F Ahmed ; Ann Hedley ; William Clark ; Danny T Huang Series Type : Expression profiling by high throughput sequencing Organism : Mus musculus. Cbl (Casitas B-lineage lymphoma) is a prominent post-translational regulator of protein tyrosine kinases (PTKs) that targets activated receptors for ubiquitination-mediated degradation.
PubMed News (NIH) 10/20/2019
Contributors : Katharina Ribbeck ; Kelsey Wheeler Series Type : Expression profiling by high throughput sequencing Organism : Pseudomonas aeruginosa. We use high-throughput sequencing to profile the response of the opportunistic mucosal pathogen Pseudomonas aeruginosa to mucins and mucin-glycans from the mucosal niche.
PubMed News (NIH) 10/20/2019
Contributor : David J Hackam Series Type : Expression profiling by high throughput sequencing Organism : Mus musculus. Toll-like receptor 4 (TLR4), the receptor of gram-negative bacterial endotoxin, is present on the intestinal epithelium and plays pivotal roles in intestinal epithelial differentiation and host defense.
PubMed News (NIH) 10/20/2019
Contributors : Vinay Parikh ; Yin-Fei Tan ; Eric Ross ; Michael Slifker Series Type : Expression profiling by high throughput sequencing Organism : Rattus norvegicus. We investigated how cognitive stimulation impacts gene expression in the prefrontal cortex (PFC), a brain region known to regulate higher cognitive functions including the control of attention, in young and aged rats.
PubMed News (NIH) 10/19/2019
Contributor : Yan Fang Series Type : Expression profiling by high throughput sequencing Organism : Mactra quadrangularis. RNA-seq provided a general overview of the gene expression profiles of the digestive glands of Mactra veneriformis exposed to 2, 2′,4,4′-tetrabromodiphenyl ether (BDE-47, a type of widely used brominated flame retardants).
PubMed News (NIH) 10/19/2019
Contributors : J Klibi ; S Li ; L Amable ; C Joseph ; S Brunet ; M Delord ; V Parietti ; J Jaubert ; J Marie ; S Karray ; G Eberl ; B Lucas ; A Toubert ; K Benlagha Series Type : Expression profiling by array Organism : Mus musculus. Invariant natural killer T cells (iNKT) expressing the retinoic acid receptor-related orphan receptor γt (RORγt) and producing IL-17 represent a minor subset of CD1d-restricted iNKT cells (iNKT17) in C57BL/6J (B6) mice.
PubMed News (NIH) 10/19/2019
Contributors : Zhang Yong ; Zhou Chuan ; Liu Xin ; Zhang Jingcheng Series Type : Expression profiling by high throughput sequencing Organism : Bos taurus. We hypothesized aberrant transcriptional silence was existed in bovine clone reprogramming as well as abnormal transcriptional activation and the result of RNA-seq confirmed this hypothesis.
PubMed News (NIH) 10/19/2019
Contributors : Li Wang ; Lu Wang Series Type : Expression profiling by high throughput sequencing Organism : Ginkgo biloba. We sequenced mRNA from Ginkgo biloba leaves grown at different developmental stages using the Illumina HiSeq4000 platform to generate the transcriptome dynamics that may serve as a gene expression profile blueprint for different response patterns during autumn leaf senescence and coloration.
PubMed News (NIH) 10/19/2019
Contributors : Terry Gaasterland ; Albert La Spada ; Chenchen Niu ; Colleen Stoyas Series Type : Expression profiling by high throughput sequencing Organism : Mus musculus. Atxn7 repeat expansion mutations lead to ataxia phenotypes. Total cerebellar RNA from mice with normal Atxn7 repeat lengths and expanded repeats (92 CAG) were sequenced to compared gene expression changes at 12 and 29 weeks of age in normal vs. expanded repeats.
PubMed News (NIH) 10/19/2019
Contributors : Yongpeng Shang ; Xiaofei Wang ; Di Qu Series Type : Expression profiling by high throughput sequencing Organism : Staphylococcus aureus. Purpose: The goals of this study are to compare the wild type and phoU1 or phoU2 gene knock out transcriptome profiling (RNA-seq) to analysis gene expression change Methods: Samples was prepared according to the Illumina RNA Sequencing Sample Preparation Guide.
PubMed News (NIH) 10/19/2019
Contributors : Shinya Tanaka ; Wataru Ise Series Type : Expression profiling by high throughput sequencing Organism : Mus musculus. We report the global gene expression in Tet2/Tet3-sufficient and -deficient B cell subsets. We found an alteration of multiple gene expressions in the absence of Tet2 and Tet3 in B cells. This study provides a basis for the comprehensive understanding of Tet function in B cells.

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